Stk17b - serine/threonine kinase 17b Gene

Rattus norvegicus

Also known as Drak2

Gene ID: 170904 | Gene type: protein coding

About Stk17b

Summary

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in apoptotic process; intracellular signal transduction; and protein autophosphorylation. Located in actin Cytoskeleton and nucleus. Orthologous to human STK17B (serine/threonine kinase 17b). [provided by Alliance of Genome Resources, Apr 2022]

Stk17b Products(1)

mRNA	Protein	Name
NM_133392.1	NP_596883.1	serine/threonine-protein kinase 17B

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATP binding	IDA IDA: Inferred from direct assay	11481038	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	11481038	RGD
enables protein kinase activity	IDA IDA: Inferred from direct assay	12966074	RGD
enables protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	11481038	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	11481038	RGD
involved in intracellular signal transduction	IDA IDA: Inferred from direct assay	11481038	RGD
involved in programmed cell death	IDA IDA: Inferred from direct assay	11481038	RGD
involved in protein autophosphorylation	IDA IDA: Inferred from direct assay	12966074	RGD
involved in protein phosphorylation	IDA IDA: Inferred from direct assay	11481038	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in actin cytoskeleton	IMP IMP: Inferred from mutant phenotype	11481038	RGD
located in nucleus	IDA IDA: Inferred from direct assay	11481038	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/threonine-protein kinase 17B

DAP kinase-related apoptosis-inducing protein kinase 2	death-associated protein kinase-related 2
serine/threonine kinase 17b (apoptosis-inducing)

Stk17b Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Stk17b	Q91XS8	Rhov	Rattus norvegicus	Q9Z1Y0	Y2H	11481038
Intra	Stk17b	Q91XS8	Chp1	Rattus norvegicus	P61023	IF	21374135
Intra	Stk17b	Q91XS8	Chp1	Rattus norvegicus	P61023	Y2H	21374135
Intra	Stk17b	Q91XS8	Chp1	Rattus norvegicus	P61023	Pull Down	12966074

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148062	RSS0680		98.03%	Unkown
HY-156350	SGC-STK17B-1	Inhibitor	98.5%	Unkown
HY-RS13925	STK17B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Stk17b	NCBI	NCBI:9262

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