2. Gene
  3. Cdc37 - cell division cycle 37, HSP90 cochaperone Gene

Cdc37 - cell division cycle 37, HSP90 cochaperone Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 114562 | Gene type: protein coding

About Cdc37

Summary

Enables chaperone binding activity; protein C-terminus binding activity; and protein kinase binding activity. Involved in regulation of cell cycle. Located in cytoplasm and ruffle membrane. Part of protein-containing complex. Orthologous to human CDC37 (cell division cycle 37, HSP90 cochaperone). [provided by Alliance of Genome Resources, Apr 2022]

Cdc37 Products(1)

mRNA Protein Name
NM_053743.2 NP_446195.2 hsp90 co-chaperone Cdc37
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23428871 RGD
enables protein kinase B binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables protein-folding chaperone binding IPI
IPI: Inferred from physical interaction
16335536 RGD
enables transcription corepressor binding IPI
IPI: Inferred from physical interaction
8945638 RGD
Cellular Component GO Annotation Evidence Reference Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
16335536 RGD
located in ruffle membrane IDA
IDA: Inferred from direct assay
16335536 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hsp90 co-chaperone Cdc37

CDC37 (cell division cycle 37 S. cerevisiae homolog)

cell division cycle 37 homolog

hsp90 chaperone protein kinase-targeting subunit

p50Cdc37

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N1986 Cucurbitacin D 99.91% Unkown
HY-139301 DDO-5936 Inhibitor 99.20% Unkown
HY-144650 Hsp90-Cdc37-IN-3 98.09% Unkown
HY-111414 Hsp90-Cdc37-IN-1 Inhibitor 99.66% Unkown
HY-N3417 Kongensin A ≥98.0% Unkown
HY-119906 Conglobatin 95.48% Unkown
HY-130624 Hsp90-Cdc37-IN-2 / Unkown
HY-169947 DDO-6079 Inhibitor / Unkown
HY-RS02297 CDC37 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02298 CDC37L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17502 Cdc37 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23959 Cdc37 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdc37 NCBI NCBI:11140
Mus musculus Cdc37 NCBI NCBI:12539