2. Gene
  3. Cdc20 - cell division cycle 20 Gene

Cdc20 - cell division cycle 20 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p55CDC; 2310042N09Rik

Gene ID: 107995 | Gene type: protein coding

About Cdc20

Summary

Predicted to enable several functions, including anaphase-promoting complex binding activity; histone deacetylase binding activity; and protein C-terminus binding activity. Involved in positive regulation of synapse maturation and positive regulation of synaptic plasticity. Acts upstream of or within mitotic sister chromatid cohesion; mitotic spindle assembly; and regulation of meiotic nuclear division. Predicted to be located in several cellular components, including centrosome; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including brain; early conceptus; female reproductive system; hemolymphoid system; and trigeminal ganglion. Orthologous to human CDC20 (cell division cycle 20). [provided by Alliance of Genome Resources, Apr 2022]

Cdc20 Products(1)

mRNA Protein Name
NM_023223.2 NP_075712.2 cell division cycle protein 20 homolog
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15280373 MGI
Biological Process GO Annotation Evidence Reference Source
involved in metaphase/anaphase transition of cell cycle IDA
IDA: Inferred from direct assay
32666501 MGI
involved in metaphase/anaphase transition of meiosis I IDA
IDA: Inferred from direct assay
32666501 MGI
acts upstream of or within mitotic metaphase IMP
IMP: Inferred from mutant phenotype
17325031 MGI
acts upstream of or within mitotic sister chromatid cohesion IGI
IGI: Inferred from genetic interaction
17325031 MGI
acts upstream of or within mitotic spindle assembly IMP
IMP: Inferred from mutant phenotype
17325031 MGI
involved in positive regulation of synapse maturation IDA
IDA: Inferred from direct assay
19900895 MGI
involved in positive regulation of synaptic plasticity IDA
IDA: Inferred from direct assay
19900895 MGI
acts upstream of or within regulation of meiotic nuclear division IGI
IGI: Inferred from genetic interaction
16456547 MGI
Cellular Component GO Annotation Evidence Reference Source
located in centrosome IDA
IDA: Inferred from direct assay
34298015 MGI
located in kinetochore IDA
IDA: Inferred from direct assay
32666501 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell division cycle protein 20 homolog

cell division cycle 20 homolog

mmCdc20

Cdc20 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Cdc20 Q9JJ66 Fbxo43 Mus musculus Q8CDI2
Anti Bait CoIP
16456547
Intra
Cdc20 Q9JJ66 Sirt2 Mus musculus Q8VDQ8
Anti Bait CoIP
22014574
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-110287 Apcin 99.62% Unkown
HY-130257 CP5V Inhibitor 99.31% Unkown
HY-100341 M2I-1 Inhibitor ≥98.0% Unkown
HY-130841 Apcin-A Inhibitor ≥98.0% Unkown
HY-13255 TAME Inhibitor 99.51% Unkown
HY-116006 Bis-PEG5-acid 99.90% Unkown
HY-13255A TAME hydrochloride Inhibitor 98.31% Unkown
HY-131959 (S,R,S)-AHPC-PEG5-Boc 95.29% Unkown
HY-RS02288 CDC20 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-161257 CDC20-IN-1 Inducer / Unkown
HY-172401 CDC20-IN-2 / Unkown
HY-RS02289 CDC20B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16827 Cdc20 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23269 Cdc20 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W614725 Apcin-A monohydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdc20 NCBI NCBI:991