2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Efmirenpase alfa

Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research.

For research use only. We do not sell to patients.

Efmirenpase alfa

Efmirenpase alfa Chemical Structure

CAS No. : 2770242-54-9

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Efmirenpase alfa Related Antibodies

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Description

Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research[1][2].

Isotype

human E-NPP1 fused via peptide linker to a human immunoglobulin G1 (IgG1) Fc fragment
Species Reactivity

Human
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
CAS No.
SMILES

N/A
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Efmirenpase alfa Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Efmirenpase alfa2770242-54-9Phosphodiesterase (PDE)Fusion proteinFc-ENPP1Enzyme replacement therapyArterial calcificationHypophosphatemic ricketsInhibitorinhibitorinhibit

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