2. JAK/STAT Signaling NF-κB PI3K/Akt/mTOR Anti-infection Stem Cell/Wnt MAPK/ERK Pathway
  3. MEK Akt NF-κB STAT Bacterial Antibiotic ERK PI3K
  4. DZ2002 (Standard)

DZ2002 (Standard) is the analytical standard of DZ2002. This product is intended for research and analytical applications. DZ2002 is an orally active, reversible and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), with good immunosuppressive activity. DZ2002 prevents the development of experimental dermal fibrosis by reversing the profibrotic phenotype of various cell types. DZ2002 can be used in studies of autoimmune diseases such as lupus syndrome and systemic sclerosis.

For research use only. We do not sell to patients.

DZ2002 (Standard) Chemical Structure

DZ2002 (Standard) Chemical Structure

CAS No. : 33231-14-0

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DZ2002 (Standard)33231-14-0MEKAktNF-κBSTATBacterialAntibioticERKPI3KMitogen-activated protein kinase kinaseMAPKKMAP2KPKBProtein kinase BNuclear factor-κBNuclear factor-kappaBExtracellular signal regulated kinasesPhosphoinositide 3-kinasesplenocytesimmunosuppressionTHP-1macrophageslupus syndromesystemic sclerosisInhibitorinhibitorinhibit

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