1. Disease Areas
  2. Inflammation or Immune System Disease Digestive System Disease
  3. Digestive System Inflammation
  4. Pancreatitis

Pancreatitis

Pancreatitis is inflammation of the pancreas, a vital gland located behind the stomach that produces digestive enzymes and hormones regulating blood sugar. It can manifest as acute pancreatitis, characterized by sudden onset and often caused by gallstones or alcohol abuse, or chronic pancreatitis, which develops over time due to prolonged inflammation, commonly linked to long-term alcohol use or genetic factors. Symptoms typically include severe upper abdominal pain radiating to the back, nausea, vomiting, fever, and abdominal tenderness. The condition may lead to serious complications such as pancreatic necrosis, pseudocysts, infection, bleeding, and diabetes if untreated. Management involves hospitalization for intravenous fluids, pain control, nutritional support, and addressing underlying causes. Early diagnosis and intervention are crucial to prevent progression and reduce mortality risk.

References:

Pancreatitis (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-160789
    C3001a 2415154-29-7
    C3001a is a selective TREK-1 and TREK-2 channel activator with EC50 values of 12.81 μM and 11.31 μM, respectively. C3001a does not affect other two-pore domain K+ (K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a can be used for the study of pain and pancreatitis.
    C3001a