2. Disease Areas
  3. Infection
  4. Bacterial Infection
  5. Mycobacterium Tuberculosis Infection

Mycobacterium Tuberculosis Infection

Mycobacterium tuberculosis infection causes tuberculosis, a chronic infectious disease primarily targeting the lungs. This acid-fast bacillus exhibits virulence through mechanisms enabling it to evade host immune destruction, leading to latent infection. It survives diverse host stressors—including acidic pH, hypoxia, immune responses, metal toxicity, and heat shock—by deploying specialized proteins and stress response systems. Key survival strategies include resistance to acidic and hypoxic conditions within macrophages, utilization of heat shock proteins (e.g., Hsp70, Hsp22.5, HspR, Acr2) for thermal tolerance, and acquisition of essential iron via siderophores like mycobactins and carboxymycobactins. These adaptations allow M. tuberculosis to persist and establish long-term infection in the human host.

Mycobacterium Tuberculosis Infection (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-176909
    Farnesyl phosphoryl-β-D-ribose 852384-00-0
    Farnesyl phosphoryl-β-D-ribose is a phosphorylated sugar derivative that belongs to the class of polyprenylphosphoryl sugars. Farnesyl phosphoryl-β-D-ribose can be used for the study of Mycobacterium tuberculosis infection.
    Farnesyl phosphoryl-β-D-ribose
  • HY-178436
    Antituberculosis agent-16
    Antituberculosis agent-16 is an orally active antituberculosis agent. Antituberculosis agent-16 exhibits stable antituberculosis activity with a MIC of 0.48 μg/mL against Mycobacterium tuberculosis H37Rv sensitive strain and 0.49 μg/mL against multidrug-resistant strain 14862. Antituberculosis agent-16 shows high Caco-2 permeability. Antituberculosis agent-16 can be used for the research of infection.
    Antituberculosis agent-16