2. Disease Areas
  3. Inflammation or Immune System Disease
  4. Chronic Disease and Inflammation

Chronic Disease and Inflammation

Chronic inflammation is a key contributor to the development and progression of numerous chronic diseases, including cardiovascular disease, chronic kidney disease, diabetes, non-alcoholic fatty liver disease, cancer, autoimmune disorders, and neurodegenerative and mental health conditions. It not only results from these diseases but also actively participates in their underlying mechanisms, influencing both pathogenesis and potential therapeutic interventions. For instance, genetic mutations associated with clonal hematopoiesis of indeterminate potential (CHIP) enhance inflammatory gene expression, significantly increasing the risk of coronary artery disease, highlighting the central role of inflammation in chronic disease etiology.

 

Chronic Disease and Inflammation (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19173
    CE-1037 150493-09-7
    CE-1037 (MDL 201,404YA) is a selective inhibitor of human neutrophil elastase (HNE) (Ki: 0.45 nM). CE-1037 prevents the pulmonary hemorrhage induced by intratracheal instillation of HNE. CE-1037 can be used for research of pulmonary diseases, such as COPD.
    CE-1037