Cytokeratin 15 Antibody (YA3847)

Cytokeratin 15 Antibody (YA3847) is a mouse-derived and non-conjugated IgG2a antibody, targeting to KRT15. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

Cytokeratins (CK) are keratin proteins exclusively found in epithelial tissues, classified as type I (acidic) and type II (basic). As the largest subgroup of intermediate filaments, they form the eukaryotic cytoskeleton alongside other filaments, functioning in epithelial integrity maintenance, injury protection, and cellular communication. Expressed in pairs and numbered 1–20 by molecular weight/isoelectric point, they include simple epithelial types (e.g., CK7, CK8, CK18–20) and complex types (e.g., cutaneous CK5/6, CK10, CK14–15). An alternative system categorizes acidic type I (low MW, CK9–20) and basic type II (high MW, CK1–8). Monoclonal antibodies with varying specificity target these proteins. Released during epithelial stress, Cytokeratins are detectable via commercial UBC Rapid assays (ELISA/point-of-care), showing 59.3% sensitivity and 86.1% specificity, particularly for primary high-grade tumors. by similar: UBC Rapid is developed by IDL Biotech AB.

P19012

Predicted band size: 49 kDa; Observed band size: 45 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG2a

Purified recombinant fragment of KRT15 expressed in E. Coli.