2. Neuronal Signaling Cell Cycle/DNA Damage
  3. AAK1 Cyclin G-associated Kinase (GAK)
  4. AAK1-IN-8

AAK1-IN-8 (Compound 18) is a pan-NAK inhibitor. AAK1-IN-8 inhibits AAK1 and GAK (EC50 values are 50 and 190 nM, respectively). AAK1-IN-8 inhibits the phosphorylation of AP2-µ2 subunit at T156.

For research use only. We do not sell to patients.

AAK1-IN-8 Chemical Structure

AAK1-IN-8 Chemical Structure

CAS No. : 2969205-90-9

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AAK1-IN-8 Related Antibodies

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Description

AAK1-IN-8 (Compound 18) is a pan-NAK inhibitor. AAK1-IN-8 inhibits AAK1 and GAK (EC50 values are 50 and 190 nM, respectively). AAK1-IN-8 inhibits the phosphorylation of AP2-µ2 subunit at T156[1].

Molecular Weight

429.47

Formula

C24H23N5O3
CAS No.
SMILES

O=C(C1=CC=C2C=C1OCCOCC/N=C3C=CN4N=CC2=C4N\3)NCC5=CC=CC=C5
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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AAK1-IN-8 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AAK1-IN-82969205-90-9AAK1Cyclin G-associated Kinase (GAK)Adaptor-associated Kinase 1AP2-associated kinase 1Auxilin 2NAKAP2-μ2AntiviralSARS-CoV-2Inhibitorinhibitorinhibit

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