2. Signaling Pathways
  3. Immunology/Inflammation
  4. TREM receptor
  5. TREM receptor Isoform

TREM receptor

 

TREM receptor Related Products (10):

Cat. No. Product Name Effect Purity
  • HY-P3211A
    Nangibotide TFA
    		99.86%
    Nangibotide TFA (LR12 TFA) is a synthetic peptide and TREM-1 receptor inhibitor. Nangibotide TFA inhibits NF-κB and NLRP3 inflammasome activation and reduces the release of pro-inflammatory factors (such as IL-1β, IL-8). Nangibotide TFA inhibits Apoptosis. Nangibotide TFA reduces excessive inflammatory responses and protects tissues (liver, lung) from damage. Nangibotide TFA can be used in the researches for myocardial ischemia-reperfusion injury, septic shock, acute lung injury, osteoarthritis, and acute liver failure.
  • HY-P990043
    Iluzanebart
    		Agonist 98.63%
    Iluzanebart is a human monoclonal IgG1 antibody and is the agonist antibody for human TREM2 (hTREM2). Iluzanebart improves the survival and function of microglia by activating the TREM2 signaling pathway to compensate for the loss of CSF1R function. Iluzanebart can be used for research of adult-onset leukoencephalopathy associated with CSF1R (colony stimulating factor 1 receptor) (CSF1R-ALSP).
  • HY-148095
    TREM2 agonist-2
    		Agonist 99.93%
    TREM2 agonist-2 (I-192) is an orally active triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50<0.05 μM).
  • HY-P3211B
    Nangibotide scrambled peptide
    		Control 98.03%
    Nangibotide scrambled peptide (LR12-scr) is a scrambled control peptide composed of the same amino acids from LR12 (Nangibotide; HY-P3211) but in a random sequence (YQDVELCETGED).
  • HY-P990651
    PY314
    PY314 is a humanized antibody expressed in CHO, targeting TREM2. PY314 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for PY314 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-P10938
    LP17 (human)
    		Inhibitor
    LP17 (human) is a TREM1 antagonist peptide with anti-inflammatory and anti-cancer effects.
  • HY-P11077
    LQEEDAGEYGCMVDGAR
    		Inhibitor
    LQEEDAGEYGCMVDGAR, a 17-aa peptide, is a TREM-1 inhibitor. LQEEDAGEYGCMVDGAR shows anti-inflammatory effects that can reduce the secretion of pro-inflammatory cytokines induced by Lipopolysaccharides (HY-D1056) (LPS). LQEEDAGEYGCMVDGAR can be used for the study of sepsis.
  • HY-P3211
    Nangibotide
    		98.27%
    Nangibotide (LR12) is a synthetic peptide and TREM-1 receptor inhibitor. Nangibotide inhibits NF-κB and NLRP3 inflammasome activation and reduces the release of pro-inflammatory factors (such as IL-1β, IL-8). Nangibotide inhibits Apoptosis. Nangibotide reduces excessive inflammatory responses and protects tissues (liver, lung) from damage. Nangibotide can be used in the researches for myocardial ischemia-reperfusion injury, septic shock, acute lung injury, osteoarthritis, and acute liver failure.
  • HY-P10088
    Mouse TREM-1 SCHOOL peptide, control
    		Control
    Mouse TREM-1 SCHOOL peptide, control is a negative control of Mouse TREM-1 SCHOOL peptide.
  • HY-P991174
    Anti-TREM2 Antibody (AL2p-58)
    		Inhibitor
    Anti-TREM2 Antibody (AL2p-58) is a humanized IgG1 monoclonal antibody that targets TREM2. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).