2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (7753):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-107738R
    Guggulsterone (Standard)
    Guggulsterone (Standard) is the analytical standard of Guggulsterone (HY-107738). This product is intended for research and analytical applications. Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively.
    Guggulsterone (Standard)
  • HY-17485R
    Alminoprofen (Standard)
    Alminoprofen (Standard) is the analytical standard of Alminoprofen. This product is intended for research and analytical applications. Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory agent (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2.
    Alminoprofen (Standard)
  • HY-14281R
    Trilostane (Standard)
    Trilostane (Standard) is the analytical standard of Trilostane. This product is intended for research and analytical applications. Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer.
    Trilostane (Standard)
  • HY-W130190R
    Iomeprol hydrolysate-1 (Standard)
    Iomeprol hydrolysate-1 (Standard) is the analytical standard of Iomeprol hydrolysate-1. This product is intended for research and analytical applications. Iomeprol hydrolysate-2 (compound A) is iomeprol hydrolyzate, a key intermediate in the production of Iodixanol (HY-B1426) and Iohexol (HY-B0594) X-ray contrast agents.
    Iomeprol hydrolysate-1 (Standard)
  • HY-N1374R
    Magnolin (Standard)
    Magnolin (Standard) is the analytical standard of Magnolin. This product is intended for research and analytical applications. Magnolin, a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
    Magnolin (Standard)
  • HY-W070184R
    5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (Standard)
    5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (Standard) is the analytical standard of 5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol. This product is intended for research and analytical applications.
    5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (Standard)
  • HY-Y1011R
    2-Ethylhexan-1-ol (Standard)
    2-Ethylhexan-1-ol (Standard) is the analytical standard of 2-Ethylhexan-1-ol. This product is intended for research and analytical applications.
    2-Ethylhexan-1-ol (Standard)
  • HY-103565AR
    AMN082 free base (Standard)
    AMN082 (free base) (Standard) is the analytical standard of AMN082 (free base). This product is intended for research and analytical applications. AMN082 free base, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 free base potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 free base shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects.
    AMN082 free base (Standard)
  • HY-N7141R
    Spiramycin I (Standard)
    Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic.
    Spiramycin I (Standard)
  • HY-148286R
    Gentamicin C1a (Standard)
    Gentamicin C1a (Standard) is the analytical standard of Gentamicin C1a. This product is intended for research and analytical applications. Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex.
    Gentamicin C1a (Standard)
  • HY-Z6448R
    N-(4-(4-Acetamido-2-hydroxyphenoxy)phenyl)acetamide (Paracetamol Impurity) (Standard)
    N-(4-(4-Acetamido-2-hydroxyphenoxy)phenyl)acetamide (Paracetamol Impurity) (Standard)
  • HY-W010058R
    2-Methylbenzenesulfonamide (Standard)
    2-Methylbenzenesulfonamide (Standard) is the analytical standard of 2-Methylbenzenesulfonamide. This product is intended for research and analytical applications.
    2-Methylbenzenesulfonamide (Standard)
  • HY-W010311R
    1-(Chloromethyl)-4-methylbenzene (Standard)
    1-(Chloromethyl)-4-methylbenzene (Standard) is the analytical standard of 1-(Chloromethyl)-4-methylbenzene. This product is intended for research and analytical applications.
    1-(Chloromethyl)-4-methylbenzene (Standard)
  • HY-B2169R
    Melperone (Standard)
    Melperone (Standard) is the analytical standard of Melperone (HY-B2169). This product is intended for research and analytical applications. Melperone is a butyrophenone with atypical antipsychotic properties. Melperone is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, respectively. Melperone has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values ​​of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone is also a CYP2D6 inhibitor. Melperone can be used for the study of schizophrenia, and agitation in the elderly.
    Melperone (Standard)
  • HY-101869R
    MK-0343 (Standard)
    MK-0343 (Standard) is the analytical standard of MK-0343. This product is intended for research and analytical applications. MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic.
    MK-0343 (Standard)
  • HY-N2518R
    Agnuside (Standard)
    Agnuside (Standard) is the analytical standard of Agnuside. This product is intended for research and analytical applications. Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo.
    Agnuside (Standard)
  • HY-B0920R
    Tolazamide (Standard)
    Tolazamide (U-17835) (Standard) is the analytical standard of Tolazamide. This product is intended for research and analytical applications. Tolazamide is an orally active sulfonylurea agent that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (IC50 = 4.2 µM in HEK293 cells transfected with the human receptor). Tolazamide has anti-diabetic properties. Tolazamide can lower blood glucose in sulfonylurea class. Tolazamide decreases insulin dose while continuing to maintain adequate metabolic control. Tolazamide is able to improve or normalize hyperglycemia and HbA.
    Tolazamide (Standard)
  • HY-B0372AR
    Bromhexine hydrochloride (Standard)
    Bromhexine (hydrochloride) (Standard) is the analytical standard of Bromhexine (hydrochloride). This product is intended for research and analytical applications. Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions.
    Bromhexine hydrochloride (Standard)
  • HY-W414840R
    Platinum, dichloro(1,2-cyclohexanediamine-n,n')-, [sp-4-2-(1r-trans)]- (Standard)
    Platinum, dichloro(1,2-cyclohexanediamine-n,n')-, [sp-4-2-(1r-trans)]- (Standard) is the analytical standard of Platinum, dichloro(1,2-cyclohexanediamine-n,n')-, [sp-4-2-(1r-trans)]-. This product is intended for research and analytical applications.
    Platinum, dichloro(1,2-cyclohexanediamine-n,n')-, [sp-4-2-(1r-trans)]- (Standard)
  • HY-14944R
    Homoharringtonine (Standard)
    Homoharringtonine (Standard) is the analytical standard of Homoharringtonine. This product is intended for research and analytical applications. Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.
    Homoharringtonine (Standard)