2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (7752):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17423R
    Abacavir (Standard)
    Abacavir (Standard) is the analytical standard of Abacavir. This product is intended for research and analytical applications. Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. Abacavir shows anticancer activity in prostate cancer cell lines. Abacavir can trespass the blood-brain-barrier and suppresses telomerase activity.
    Abacavir (Standard)
  • HY-17357R
    Nepafenac (Standard)
    Nepafenac (AHR 9434; AL 6515) (Standard) is the analytical standard of Nepafenac (HY-17357). This product is intended for research and analytical applications. Nepafenac, a nonsteroidal anti-inflammatory agent, is a topically administered COX-2 inhibitor with an IC50 of 0.12 μM. Nepafenac exhibits only weak COX-1 inhibitory activity (IC50 = 64.3 μM). Nepafenac possesses unique prodrug properties, which enable it to rapidly convert into the active metabolite Amfenac (HY-17479) in the ocular tissues, thereby achieving high concentrations in the retina and choroid. Nepafenac reduces inflammation and pain by inhibiting the activity of cyclooxygenase (COX) enzymes and thereby decreasing the production of prostaglandin PGE₂. Nepafenac can delay the metastasis of uveal melanoma (UM) in rabbit eyes. Nepafenac is mainly used for pain management and inflammation control after ophthalmic surgeries.
    Nepafenac (Standard)
  • HY-176107
    α-(4-Methylpiperidino)isohexanophenone hydrochloride
    α-(4-Methylpiperidino)isohexanophenone (hydrochloride) (α-Pipecolinoisohexanophenone (hydrochloride)) is a drug derivative.
    α-(4-Methylpiperidino)isohexanophenone hydrochloride
  • HY-B1470R
    Azaperone (Standard)
    Azaperone (Standard) is the analytical standard of Azaperone. This product is intended for research and analytical applications. Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
    Azaperone (Standard)
  • HY-40352R
    N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (Standard)
    N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (Standard) is the analytical standard of N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine. This product is intended for research and analytical applications.
    N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (Standard)
  • HY-W130436R
    2,2-Dimethyl-4,7-dihydro-1,3-dioxepine (Standard)
    2,2-Dimethyl-4,7-dihydro-1,3-dioxepine (Standard)
  • HY-W011792R
    Diacetone-β-D-fructose (Standard)
    Diacetone-β-D-fructose (Standard) is the analytical standard of Diacetone-β-D-fructose. This product is intended for research and analytical applications. Diacetone-β-D-fructose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Diacetone-β-D-fructose (Standard)
  • HY-N7007R
    Sclareol glycol (Standard)
    Fluazifop (Standard) is the analytical standard of Fluazifop. This product is intended for research and analytical applications. Fluazifop is a grass-selective herbicide via inhibiting acetyl-CoA carboxylase.
    Sclareol glycol (Standard)
  • HY-N2574R
    Gitogenin (Standard)
    Gitogenin (Standard) is the analytical standard of Gitogenin. This product is intended for research and analytical applications. Gitogenin is a natural steroid isolated from the whole plant of Tribulus longipetalus. Gitogenin is a selective inhibitor of UDP-glucuronosyltransferase 1A4 (UGT1A4) and enzyme α-glucosidase with IC50 values of 0.69 μM (use trifluoperazine as a substrate) and 37.2 μM, respectively, and does not inhibit the activities of major human cytochrome P450 isoforms.
    Gitogenin (Standard)
  • HY-N7916R
    (-)-Menthone (Standard)
    (-)-Menthone (Standard) is the analytical standard of (-)-Menthone. This product is intended for research and analytical applications. (-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone.Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm (-)-Menthone is 27.67% and 94.92%.
    (-)-Menthone (Standard)
  • HY-W009123R
    Erucamide (Standard)
    Erucamide (Standard) is the analytical standard of Erucamide. This product is intended for research and analytical applications. Erucamide inhibits intestinal diarrhea.Erucamide also regulates the volume of body fluids in other organs. Erucamide has the ability to promote angiogenesis.
    Erucamide (Standard)
  • HY-100585R
    Splitomicin (Standard)
    Splitomicin (Standard) is the analytical standard of Splitomicin. This product is intended for research and analytical applications. Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD+-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 μM.
    Splitomicin (Standard)
  • HY-W015786R
    4-Ethoxyphenol (Standard)
    L-Amoxicillin (Standard) is the analytical standard of L-Amoxicillin. This product is intended for research and analytical applications. L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application.
    4-Ethoxyphenol (Standard)
  • HY-W012572R
    D-Histidine (Standard)
    D-Histidine (Standard) is the analytical standard of D-Histidine (HY-W012572). This product is intended for research and analytical applications. D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu2+).
    D-Histidine (Standard)
  • HY-100954R
    2,4-Diamino-6-hydroxypyrimidine (Standard)
    2,4-Diamino-6-hydroxypyrimidine (Standard) is the analytical standard of 2,4-Diamino-6-hydroxypyrimidine. This product is intended for research and analytical applications. 2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production.
    2,4-Diamino-6-hydroxypyrimidine (Standard)
  • HY-131926R
    EDTA iron sodium (Standard)
    EDTA (iron sodium) (Standard) is the analytical standard of EDTA (iron sodium). This product is intended for research and analytical applications. EDTA iron sodium (NaFeEDTA; Sodium iron EDTA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    EDTA iron sodium (Standard)
  • HY-B0380AR
    Trimebutine maleate (Standard)
    Trimebutine maleate (Standard) is the analytical standard of Trimebutine maleate (HY-B0380A). This product is intended for research and analytical applications. Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine maleate inhibits L-type Ca2+ channels and large-conductance calcium-activated potassium channels (BKCa channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine maleate also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine maleate also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine maleate also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS).
    Trimebutine maleate (Standard)
  • HY-114911R
    Feprazone (Standard)
    Feprazone (Standard) is the analytical standard of Feprazone. This product is intended for research and analytical applications. Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity.
    Feprazone (Standard)
  • HY-B1344R
    Oxantel pamoate (Standard)
    Oxantel pamoate (Standard) (Oxantel embonate (Standard)) is the analytical standard of Oxantel pamoate (HY-B1344). This product is intended for research and analytical applications. Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM).
    Oxantel pamoate (Standard)
  • HY-12887R
    Piclamilast (Standard)
    Piclamilast (Standard) is the analytical standard of Piclamilast. This product is intended for research and analytical applications. Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively.
    Piclamilast (Standard)