1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. PNPLA3
  4. PNPLA3 Modulator

PNPLA3 Modulator

PNPLA3 Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-N1967
    Dihydrocurcumin
    Modulator 99.77%
    Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways.
  • HY-159656
    PNPLA3 modifier 1
    Modulator
    PNPLA3 modifier 1 (compound 10) is a Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifier, with a geometric mean EC50 of 4.9 nM.