2. Signaling Pathways
  3. Others
  4. mRNA

mRNA

messenger RNA

 

mRNA Related Products (319):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-174505
    Human YAP1 mRNA
    Human YAP1 mRNA encodes the human Yes1 associated transcriptional regulator (YAP1) protein, a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. YAP1 is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment.
    Human YAP1 mRNA
  • HY-174623
    Human IL20RA mRNA
    Human IL20RA mRNA encodes the human interleukin 20 receptor subunit alpha (IL20RA) protein, a member of the type II cytokine receptor family. IL20RA is a subunit of the receptor for interleukin 20, a cytokine that may involve in epidermal function.
    Human IL20RA mRNA
  • HY-174764
    Human CCL19 mRNA
    Human CCL19 mRNA encodes the human C-C motif chemokine ligand 19 (CCL19) protein, a cytokine that may play a role in normal lymphocyte recirculation and homing. CCL19 also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs.
    Human CCL19 mRNA
  • HY-174569
    Human NFKB1 mRNA
    Human NFKB1 mRNA encodes the human nuclear factor kappa B subunit 1 (NFKB1) protein, a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral infection.
    Human NFKB1 mRNA
  • HY-174530
    Human TGFBR2 mRNA
    Human TGFBR2 mRNA encodes the human transforming growth factor beta receptor 2 (TGFBR2) protein, a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. TGFBR2/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis.
    Human TGFBR2 mRNA
  • HY-174704
    Human FGF18 mRNA
    Human FGF18 mRNA encodes the human fibroblast growth factor 18 (FGF18) protein, a member of the fibroblast growth factor (FGF) family. FGF18 probably plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. It is also required for normal ossification and bone development.
    Human FGF18 mRNA
  • HY-174676
    Human GATA2 mRNA
    Human GATA2 mRNA encodes the human GATA binding protein 2 (GATA2) protein, a member of the GATA family of zinc-finger transcription factors. GATA2 plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages.
    Human GATA2 mRNA
  • HY-174779
    Human AREG mRNA
    Human AREG mRNA encodes the human amphiregulin (AREG) protein, a member of the epidermal growth factor family. AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development.
    Human AREG mRNA
  • HY-174652
    Human IGFBP1 mRNA
    Human IGFBP1 mRNA encodes the human insulin like growth factor binding protein 1 (IGFBP1) protein, a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP1 is important in cell migration and metabolism.
    Human IGFBP1 mRNA
  • HY-174792
    Cre-T2A-GFP mRNA
    The Cre-T2A-GFP mRNA is a capped and polyadenylated messenger RNA encoding a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP).
    Cre-T2A-GFP mRNA
  • HY-174493
    Firefly luciferase mRNA (5moU)
    Firefly luciferase (FLuc) mRNA (5moU) expresses a luciferase protein, originally isolated from the firefly, Photinus pyralis. FLuc is commonly used in mammalian cell culture to measure both gene expression and cell viability. It emits bioluminescence in the presence of the substrate, luciferin.
    Firefly luciferase mRNA (5moU)
  • HY-174705
    Human FGF17 mRNA
    Human FGF17 mRNA encodes the human fibroblast growth factor 17 (FGF17) protein, a member of the fibroblast growth factor (FGF) family. FGF17 probably plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also required for normal brain development.
    Human FGF17 mRNA
  • HY-174495
    Human EPO mRNA
    Human EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.
    Human EPO mRNA
  • HY-174678
    Human FOXA3 mRNA
    Human FOXA3 mRNA encodes the human forkhead box A3 (FOXA3) protein which is thought to act as a ''pioneer'' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.
    Human FOXA3 mRNA
  • HY-174703
    Human FGF19 mRNA
    Human FGF19 mRNA encodes the human fibroblast growth factor 19 (FGF19) protein, a member of the fibroblast growth factor (FGF) family. FGF19 probably involves in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades.
    Human FGF19 mRNA
  • HY-174732
    Human CSF3 mRNA
    Human CSF3 mRNA encodes the human colony stimulating factor 3 (CSF3) protein, a member of the IL-6 superfamily of cytokines. CSF3 controls the production, differentiation, and function of granulocytes.
    Human CSF3 mRNA
  • HY-174689
    Human FGFR2 mRNA
    Human FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
    Human FGFR2 mRNA
  • HY-174551
    Human PDGFC mRNA
    Human PDGFC mRNA encodes the human platelet derived growth factor C (PDGFC) protein, a member of the platelet-derived growth factor family. PDGFC plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFC mRNA
  • HY-174629
    Human IL19 mRNA
    Human IL19 mRNA encodes the human interleukin 19 (IL19) protein, a cytokine that belongs to the IL10 cytokine subfamily. IL19 may play some important roles in inflammatory responses.
    Human IL19 mRNA
  • HY-174790
    Firefly Luciferase mRNA
    Firefly Luciferase (FLuc) mRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). FLuc is commonly used in mammalian cell culture to measure both gene expression and cell viability.
    Firefly Luciferase mRNA