2. Signaling Pathways
  3. Immunology/Inflammation
  4. Mesothelin
  5. Mesothelin Inhibitor

Mesothelin Inhibitor

Mesothelin Inhibitors (6):

Cat. No. Product Name Effect Purity
  • HY-P99006
    Amatuximab
    		Inhibitor 99.90%
    Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium.
  • HY-P99352
    Anetumab
    		Inhibitor 98.78%
    Anetumab (Anti-MSLN Antibody) is a fully humanized anti mesothelin (MSLN) IgG1 antibody. Anetumab (Anti-MSLN Antibody) can be used to synthesize the ADC molecule Anetumab ravtansine (HY-141606). Anetumab (Anti-MSLN Antibody) can be used for the research of cancer.
  • HY-P990833
    Anti-Mesothelin Antibody (YP218)
    		Inhibitor
    Anti-Mesothelin Antibody (YP218) is a kind of rabbit IgG chimeric antibody, targeting to human Mesothelin.
  • HY-P991456
    LMB-100
    		Inhibitor
    LMB-100 is a human immunotoxin targeting MSLN/Mesothelin. LMB-100 induces systemic inflammation and CD8 T cell recruitment. LMB-100 enhances the antitumor effects of anti-PD-1 antibodies in a human peripheral blood mononuclear cell transplanted mesothelioma mouse model and a syngeneic lung adenocarcinoma mouse model expressing human mesothelin. LMB-100 can be used in mesothelioma research. Recommended isotype control: Fab fused with a fragment of Pseudomonas exotoxin A.
  • HY-P991189
    AMG-305
    		Inhibitor
    AMG-305 is a humanized IgG1 monoclonal antibody targeting CDH3/MSLN.
  • HY-P990466
    Anti-Mesothelin Antibody
    		Inhibitor
    Anti-Mesothelin Antibody is a humanized antibody expressed in CHO that targets Mesothelin. The Anti-Mesothelin Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For isotype control of the Anti-Mesothelin Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).