2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Mesothelin ADC Antibody
  4. Anetumab

Anetumab  (Synonyms: Anti-MSLN Antibody)

Cat. No.: HY-P99352 Purity: 98.78%
COA
SDS
Technical Support

Anetumab (Anti-MSLN Antibody) is a fully humanized anti mesothelin (MSLN) IgG1 antibody. Anetumab (Anti-MSLN Antibody) can be used to synthesize the ADC molecule Anetumab ravtansine (HY-141606). Anetumab (Anti-MSLN Antibody) can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No. : 1954758-84-9

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Description

Anetumab (Anti-MSLN Antibody) is a fully humanized anti mesothelin (MSLN) IgG1 antibody. Anetumab (Anti-MSLN Antibody) can be used to synthesize the ADC molecule Anetumab ravtansine (HY-141606). Anetumab (Anti-MSLN Antibody) can be used for the research of cancer[1].

Isotype

Human IgG1 lambda
Recommend Isotype Controls
IC50 & Target

Mesothelin
In Vitro

Anetumab ravtansine (HY-141606) is composed of Anetumab and the microtubule-targeting toxin DM4 (HY-12454) linked by a reducible disulfide bond[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anetumab Related Antibodies
Clinical Trial
Gene ID

10232  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

143.66 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anetumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 lambda
Biological Activity
  • Immobilized Mesothelin Protein, Human (303a.a, HEK293, His, HY-P70148) can bind Anetumab. The EC50 for this effect is 4.33 ng/mL.
Purity & Documentation

Purity: 98.78%

SDS (251 KB)

COA (232 KB) SDS-PAGE (68 KB) SEC-HPLC (126 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Anetumab Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anetumab1954758-84-9Anti-MSLN AntibodyMesothelinADC AntibodyMSLNantibodyantigenADCmalignant tumorcancerInhibitorinhibitorinhibit

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