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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9978):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-167092
    SD-1077
    SD-1077 is a selectively deuterated precursor of dopamine (DA). SD-1077 can be used for the study of Parkinson's disease.
    SD-1077
  • HY-170017S
    (−)-Epigallocatechin Gallate-d3/d4
    (-)-Epigallocatechin Gallate-d3/d4 (EGCG-d3/d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma.
    (−)-Epigallocatechin Gallate-d<sub>3</sub>/d<sub>4</sub>
  • HY-14268S3
    Febuxostat-d5
    Febuxostat-d5 (TEI 6720-d5) is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout.
    Febuxostat-d<sub>5</sub>
  • HY-100442S
    Paquinimod-d5
    Paquinimod-d5 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice.
    Paquinimod-d<sub>5</sub>
  • HY-W268109S
    3-Mercaptopentan-2-one-d2
    3-Mercaptopentan-2-one-d2 is deuterated labeled 3-Mercaptopentan-2-one.
    3-Mercaptopentan-2-one-d<sub>2</sub
  • HY-14656S2
    Diltiazem-d6 hydrochloride
    Diltiazem-d6 (hydrochloride) (CRD-401-d6 (hydrochloride)) is deuterium labeled Diltiazem (hydrochloride). Diltiazem hydrochloride is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist).
    Diltiazem-d<sub>6</sub> hydrochloride
  • HY-W700927
    N-Formyl-L-leucine-d3
    N-Formyl-L-leucine-d3 (N-Formyl-S-leucine-d3) is deuterium labeled N-Formyl-L-leucine. N-Formyl-L-leucine is a leucine derivative.
    N-Formyl-L-leucine-d<sub>3</sub>
  • HY-13777S1
    Zoledronic acid-d3
    Zoledronic acid-d3 is the deuterium labeled Zoledronic acid.
    Zoledronic acid-d<sub>3</sub>
  • HY-W719722
    Chloraminophenamide-15N2
    Chloraminophenamide-15N2 is 15N labeled Chloraminophenamide.
    Chloraminophenamide-<sup>15</sup>N<sub>2</sub>
  • HY-138815S
    (S)-N-(1H-Indole-3-acetyl)tryptophan-d4
    (S)-N-(1H-Indole-3-acetyl)tryptophan-d4 is deuterium labeled (S)-N-(1H-Indole-3-acetyl)tryptophan. (S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase.
    (S)-N-(1H-Indole-3-acetyl)tryptophan-d<sub>4</sub>
  • HY-132439S
    4-Hydroxy Mepivacaine-d3
    4-Hydroxy Mepivacaine-d3 is the deuterium labeled 4-Hydroxy Mepivacaine.
    4-Hydroxy Mepivacaine-d<sub>3</sub>
  • HY-W654127
    Cytarabine-13C3 5'-monophosphate
    Cytarabine-13C3 5'-monophosphate is 13C labeled Cytarabine 5’-monophosphate.
    Cytarabine-<sup>13</sup>C<sub>3</sub> 5'-monophosphate
  • HY-W021040S
    Fludioxonil-13C3
    Fludioxonil-13C3 (CGA-173506-13C3) is 13C labeled Fludioxonil. Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells.
    Fludioxonil-<sup>13</sup>C<sub>3</sub>
  • HY-10574S1
    Rilpivirine-13C6
    Rilpivirine-13C6 (R278474-13C6) is 13C labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV.
    Rilpivirine-<sup>13</sup>C<sub>6</sub>
  • HY-167596S
    C18:0-d7 GD2 Ceramide (d18:1/18:0-d7)
    C18:0-d7 GD2 Ceramide (d18:1/18:0-d7) is deuterium labeled C18:0 GD2 Ceramide (d18:1/18:0).
    C18:0-d<sub>7</sub> GD2 Ceramide (d18:1/18:0-d<sub>7</sub>)
  • HY-W012837S
    Benzylmethylether-d2
    Benzylmethylether-d2 (Methoxymethylbenzene-d2) is the deuterium labeled (Methoxymethyl)benzene (HY-W012837).
    Benzylmethylether-d<sub>2</sub>
  • HY-W654306
    1-Palmitoyl-2-oleoyl-3-chloropropanediol-d5
    1-Palmitoyl-2-oleoyl-3-chloropropanediol-d5 is deuterium labeled 1-Palmitoyl-2-oleoyl-3-chloropropanediol. 1-Palmitoyl-2-oleoyl-3-chloropropanediol is an ester product.
    1-Palmitoyl-2-oleoyl-3-chloropropanediol-d<sub>5</sub>
  • HY-154744S
    Trimegestone sulfate pyridinium salt-13C,d3
    Trimegestone sulfate pyridinium salt-13C,d3 is 13C and deuterated labeled Trimegestone sulfate pyridinium salt.
    Trimegestone sulfate pyridinium salt-<sup>13</sup>C,d<sub>3</sub>
  • HY-106577S1
    Cibenzoline-d5
    Cibenzoline-d5 (Cifenline-d5) is deuterium labeled Cibenzoline. Cibenzoline is a class Ia antiarrhythmic active molecule with low anticholinergic activity. Cibenzoline is a KATP channel inhibitor, acting through the pore forming subunit Kir6.2, with an IC50 of 22.2 μM. Cibenzoline inhibits IKr and IKs currents with IC50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is used in the study of cardiac diseases. In addition, Cibenzoline can induce hypoglycemia.
    Cibenzoline-d<sub>5</sub>
  • HY-15409S2
    Empagliflozin-d6
    Empagliflozin-d6 (BI 10773-d6) is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2.
    Empagliflozin-d<sub>6</sub>