Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9979):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0280S1

Ranolazine-d₈		99.83%
Ranolazine-d₈ is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC₅₀ values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. Antianginal agent.

HY-165696S1

2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)-¹⁵N₂
2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)-¹⁵N₂ is ¹⁵N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium).

HY-W654334

9-cis-Retinol-d₅
9-cis-Retinol-d₅ is deuterium labeled 9-cis Retinol. 9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells.

HY-108325S

Brequinar-d₃
Brequinar-d₃ (DUP785-d₃) is deuterium labeled Brequinar. Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC₅₀ of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.

HY-166885S

Ceftazidime-d₆ sodium
Ceftazidime-d₆ (sodium) is deuterium labeled Ceftazidime (sodium).

HY-157059S

6-O-Desmethylprazosin-d₈ TFA
6-O-Desmethylprazosin-d₈ (TFA) is deuterium-labeled 6-O-Desmethylprazosin.

HY-W015604S1

2,3-Diethyl-5-methylpyrazine-d₇
2,3-Diethyl-5-methylpyrazine-d₇ is deuterated labeled 2,3-Diethyl-5-methylpyrazine.

HY-W654336

(S)-Rivastigmine-d₄
(S)-Rivastigmine-d₄ is deuterium labeled Rivastigmine. Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC₅₀s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.

HY-W654227

7-Hydroxy methotrexate-d₃ ammonium salt
7-Hydroxy methotrexate-d₃ (ammonium salt) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.

HY-W102356S1

Phenethyl acetate-¹³C₂
Phenethyl acetate-¹³C2 is ¹³C labeled Phenethyl acetate (HY-W102356). Phenethyl acetate (Phenethyl alcohol) is a natural product.

HY-144364S1

cis-N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine-d₃
cis-N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine-d₃ is the deuterium labeled cis-N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine.

HY-170001S

Palmitoyl-L-carnitine-d₉ chloride
Palmitoyl-L-carnitine-d₉ (chloride) is deuterium labeled Palmitoyl-L-carnitine (chloride).

HY-W127425S1

Ethyl lignocerate-d₄
Ethyl lignocerate-d₄ (Tetracosanoic acid ethyl ester-d₄)Deuterium-labeled Ethyl lignocerate (HY-W127425).

HY-163993S

GMDRWGQGTLVTVSS-(Leu-¹³C₆,¹⁵N)
GMDRWGQGTLVTVSS-(Leu-13C6,15N) is the ¹³C and ¹⁵N labeled isotope of GMDRWGQGTLVTVSS.

HY-W745661

Palmitoyldocosahexaenoyl Phosphatidylcholine-d₉
Palmitoyldocosahexaenoyl Phosphatidylcholine-d₉ (1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine-d₉) is deuterium labeled Palmitoyldocosahexaenoyl Phosphatidylcholine.

HY-132332S

cis-Hydroxy perhexiline-d₁₁
cis-Hydroxy perhexiline-d₁₁ is the deuterium labeled cis-Hydroxy perhexiline.

HY-I1111S2

Fmoc-L-Val-OH-¹³C₅,¹⁵N		98%
Fmoc-L-Val-OH-¹³C₅,¹⁵N is a ¹⁵N-labeled and ¹³C-labled Fmoc-L-Val-OH (HY-I1111). Fmoc-L-Val-OH is a valine derivative.

HY-157075S

(Z)-Rilpivirine-d₄
(Z)-Rilpivirine-d₄ (R278474-d₄; TMC278-d₄; DB08864-d₄) is deuterium-labeled (Z)-Rilpivirine.

HY-A0003S3

Lenalidomide-d₄
Lenalidomide-d₄ (CC-5013-d₄) is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.

HY-W141978S1

DL-Lysine-d₈ dihydrochloride
DL-Lysine-d₈ (dihydrochloride) is the deuterium labeled DL-Lysine.

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