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  4. Drug Isomer

Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (217):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W726667A
    (R)-(-)-Citramalic acid lithium
    (R)-(-)-Citramalic acid ((R)-Citramalate) lithium, a lithium salt of Citramalic acid, is the R enantiomer of Citramalic acid lithium. (R)-(-)-Citramalic acid lithium is involved in the metabolism of glutamate through the methylaspartate pathway. (R)-(-)-Citramalic acid lithium is promising for research of neurological disorders.
    (R)-(-)-Citramalic acid lithium
  • HY-155953
    6-epi-COTC
    6-epi-COTC is a diastereoisomer of Streptomyces metabolite with a anti-cancer activitie.
    6-epi-COTC
  • HY-137674A
    isoGTP sodium
    isoGTP (Isoguanosine-5'-O-triphosphate) sodium is an isomer of guanosine 5'-triphosphate and a phosphorylated form of Crotonoside (HY-N0071). isoGTP sodium inhibits transcription and induces T to C mutations in a reverse transcriptase assay. isoGTP sodium is promising for research of substrate specificity of phosphofructokinase and mutT homolog 1 (MTH1).
    isoGTP sodium
  • HY-19471
    (rac)-ZK-304709
    (rac)-ZK-304709 is an isoform of ZK-304709 and is an orally active multi-targeted tumor growth inhibitor that inhibits multiple cell cycle-dependent kinases (CDKs), vascular endothelial growth factor receptor kinases (VEGF-RTKs), and platelet-derived growth factor receptor kinase β (PDGF-RTKβ). (rac)-ZK-304709 can dose-dependently inhibit the proliferation and colony formation of neuroendocrine tumor (NET) cells. (rac)-ZK-304709 directly acts on NET cells by inducing G2 cell cycle arrest and apoptosis, while reducing the expression of MCL1, survivin, and HIF1α. (rac)-ZK-304709 effectively controls tumor growth by inducing apoptosis and inhibiting tumor-induced angiogenesis, and may become a potential agent for inhibiting NET.
    (rac)-ZK-304709
  • HY-106841A
    (S)-Draflazine
    (S)-Draflazine ((-)-Draflazine) is the (S)-configuration of Draflazine (HY-106841). (S)-Draflazine is a potent blocker of nucleoside transport.
    (S)-Draflazine
  • HY-133022R
    trans-2-Undecenoic acid (Standard)
    trans-2-Undecenoic acid (Standard) is the analytical standard of trans-2-Undecenoic acid. This product is intended for research and analytical applications. trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O[1].
    trans-2-Undecenoic acid (Standard)
  • HY-156717
    RE-33
    RE-33 is an analgesic compound. RE-33 has blood brain barrier penetration ability.
    RE-33
  • HY-W740803
    15-cis-Phytofluene
    15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis.
    15-cis-Phytofluene
  • HY-137862A
    (Rac)-1-Oleoyl lysophosphatidic acid
    (Rac)-1-Oleoyl lysophosphatidic acid is an isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid that can activate the LPA receptors .
    (Rac)-1-Oleoyl lysophosphatidic acid
  • HY-U00363A
    (rac)-CHEMBL333994
    (rac)-CHEMBL333994 is the racemate of CHEMBL333994 (HY-U00363). CHEMBL333994 is a potent and orally active Cholecystokinin A receptor (CCK-A receptor) antagonist, with an IC50 of 0.67 nM. CHEMBL333994 selectively antagonizes peripheral CCK receptors. CHEMBL333994 increases CCK mRNA level. CHEMBL333994 can be used for research of chronic pancreatitis.
    (rac)-CHEMBL333994
  • HY-19599A
    (Rac)-Vorozole
    (Rac)-Vorozole ((Rac)-R83842) is a racemate of Vorozole. Vorozole (HY-19599) is a potent and selective, orally active non-steroidal aromatase inhibitor.
    (Rac)-Vorozole
  • HY-128543
    Zidapamide
    Zidapamide (Compound 4a) is an isomer of indapamide (HY-B0259). Zidapamide has diuretic and natriuretic activities. Zidapamide is used in the study of hypertension.
    Zidapamide
  • HY-N15890
    Tauroisolithocholanoic acid （sodium)
    Tauroisolithocholanoic acid sodium is an isomer of the naturally occurring Taurolithocholic acid (HY-113308).
    Tauroisolithocholanoic acid （sodium)
  • HY-121582
    (E)-SI-2
    (E)-SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer.
    (E)-SI-2
  • HY-125784B
    (S)-Viloxazine hydrochloride
    (S)-Viloxazine hydrochloride is the isomer of Viloxazine hydrochloride (HY-125784). Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist，EC50 for 5-HT2C b> is 32 μM，and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research.
    (S)-Viloxazine hydrochloride
  • HY-117799C
    (±)-LY-426965 dihydrochloride
    		Control
    (±)-LY-426965 dihydrochloride is a racemate of LY-426965 (HY-117799). LY426965 is a potent 5-HT1A receptor antagonist.
    (±)-LY-426965 dihydrochloride
  • HY-125825A
    (Z)-Pseudoginsenoside Rh2
    (Z)-Pseudoginsenoside Rh2 is the (Z) isoform of Pseudoginsenoside Rh2 (HY-125825), which is synthesized from Ginsenoside Rh2, possesses anti-cancer activitied.
    (Z)-Pseudoginsenoside Rh2
  • HY-139421
    (Z)-16-(Ethylcarbamoylamino)hexadec-11-enoic acid
    (Z)-16-(Ethylcarbamoylamino)hexadec-11-enoic acid (Compound 21) is a vasorelaxant (EC50=5.7 μM) that can be used in cardiovascular disease research.
    (Z)-16-(Ethylcarbamoylamino)hexadec-11-enoic acid
  • HY-176099
    Epibenzomalvin E
    Epibenzomalvin E is an isomer of Benzmalvin E. Benzomalvin E is an indoleamine 2,3-dioxygenase inhibitor.
    Epibenzomalvin E
  • HY-W202854
    Methiopropamine 3’-thiophene isomer hydrochloride
    		Control
    Methiopropamine 3’-thiophene isomer is an isomer of Methiopropamine that has the sulfur atom of the thiophene group at the 3 position.
    Methiopropamine 3’-thiophene isomer hydrochloride