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  4. Drug Intermediate

Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (2203):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-44408
    2-(4-Bromophenoxy)ethanol
    2-(4-Bromophenoxy)ethanol is a Benzene compound and an intermediate.
    2-(4-Bromophenoxy)ethanol
  • HY-W008351R
    L-Ribose (Standard)
    L-Ribose (Standard) is the analytical standard of L-Ribose (HY-W008351). This product is intended for research and analytical applications. L-Ribose, a non-naturally occurring pentose, is an ideal starting material for use in synthesizing L-nucleosides analogues. L-Ribose can be used for the synthesis of various anticancer and antiviral agents such as Telbivudine (HY-B0017).
    L-Ribose (Standard)
  • HY-139735
    Antitumor agent-29
    Antitumor agent-29 is a novel hepatocyte-targeting antitumor proagent, which exhibits good antitumor activity and low toxic side effects.
    Antitumor agent-29
  • HY-79096S
    BOC-L-Phenylalanine-13C
    BOC-L-Phenylalanine-13C is a 13C-labeled BOC-L-Phenylalanine (HY-79096). Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent.
    BOC-L-Phenylalanine-<sup>13</sup>C
  • HY-Z9064
    1-epi-Regadenoson ethyl ester
    1-epi-Regadenoson ethyl ester is an intermediate in the synthesis of αisomer impurity of Regadenoson which is a highly selective adenosine A2A receptor agonist.
    1-epi-Regadenoson ethyl ester
  • HY-W009688
    Dibutyl maleate
    		98.80%
    Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice.
    Dibutyl maleate
  • HY-126584S
    H-Val-Val-OH-13C10,15N2 TFA
    H-Val-Val-OH-13C10,15N2 TFA (Val-val-13C10,15N2) is the 13C- and 15N-labeled H-Val-Val-OH (HY-126584). H-VAL-VAL-OH (Val-val) is a dipeptide in which two valine (Val) residues are linked by an amide bond. H-VAL-VAL-OH can be used for the synthesis of some important compounds such as Poststatin (HY-125432).
    H-Val-Val-OH-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>2</sub> TFA
  • HY-160703
    DMBA-SIL-PNP
    DMBA-SIL-PNP (Compound 5) is an intermediate used for preparing Drug-Linker Conjugates, which can be applied in cancer research.
    DMBA-SIL-PNP
  • HY-W765881
    Capecitabine 2',3'-diacetate-d11
    Capecitabine 2',3'-diacetate-d11 is the deuterium labeled Capecitabine 2',3'-diacetate (HY-W099488). Capecitabine 2',3'-diacetate (Compound 10b) is the prodrug for the antitumor agent Capecitabine (HY-B0016).
    Capecitabine 2',3'-diacetate-d<sub>11</sub>
  • HY-177482
    Pro-PTX
    Pro-PTX is an inactive prodrug of Paclitaxel (HY-B0015). Pro-PTX does not show cytotoxicity against cancer cells, such as A549, U87 and HBVP cells. Pro-PTX can be converted into Paclitaxel through dealkylation catalyzed by Pd nanosheets in agarose and alginate hydrogels.
    Pro-PTX
  • HY-148378
    5β-Dihydrocortisone acetate
    5β-Dihydrocortisone acetate can be used for the synthesis of tetrahydrocortisone 3-glucuronide.
    5β-Dihydrocortisone acetate
  • HY-174460
    pCR8
    pCR8 is a prodrug of CR8 (HY-18340). pCR8 is amphiphilic and can self-assemble into nanoparticles. pCR8 can release CR8 under the action of high concentration of H2O2 in the tumor microenvironment. CR8 is a molecular glue degrader that can effectively degrade cell cycle-related proteins and has antitumor activity. pCR8 can be used in the research of tumors such as breast cancer.
    pCR8
  • HY-W092549
    5-Hydroxyisatin
    5-Hydroxyisatin can be used to synthesize anti-cancer agents.
    5-Hydroxyisatin
  • HY-44680
    L-Cystine N-carboxyanhydride
    L-Cystine N-carboxyanhydride can be used for synthesis of polyamino acid carrier for anti-tumor agent delivery.
    L-Cystine N-carboxyanhydride
  • HY-173703
    β-Glu-PAB(CH2NH2)-Exatecan
    β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) is a topoisomerase I inhibitor. β-Glu-PAB(CH2NH2)-Exatecan binds to the topoisomerase I-DNA complex to prevent DNA strand reconnection, thereby inducing DNA breakage and cell apoptosis. β-Glu-PAB(CH2NH2)-Exatecan can be specifically cleaved by β-glucuronidase highly expressed in the tumor microenvironment to release Exatecan for cytotoxic effect. β-Glu-PAB(CH2NH2)-Exatecan is also an intermediate of Mal((3S,3aR,6S,6aR) -hexahydrofuro [3, 2-B]furan-3,6-diamine-PEG12)-β -Glu-Pab-Exatecan. β-Glu-PAB(CH2NH2)-Exatecan is promising for research of cancers.
    β-Glu-PAB(CH2NH2)-Exatecan
  • HY-N16458
    FI-3
    FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics.
    FI-3
  • HY-N3994
    16α,17α-Epoxyprogesterone
    16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). 16α,17α-Epoxyprogesterone can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds.
    16α,17α-Epoxyprogesterone
  • HY-176028
    N-Stearoyl-DPPE ammonium
    N-Stearoyl-DPPE ammonium is a type of N-acylphosphatidylethanolamine (NAPE). N-Stearoyl-DPPE ammonium is an important intermediate in the endocannabinoid biosynthesis pathway.
    N-Stearoyl-DPPE ammonium
  • HY-135380R
    Atorvastatin acetonide tert-butyl ester (Standard)
    Atorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
    Atorvastatin acetonide tert-butyl ester (Standard)
  • HY-108399
    Fingolimod impurity 3
    Fingolimod impurity 3 is an impurity of Fingolimod (HY-11063).
    Fingolimod impurity 3