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Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (2203):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W412326
    Guaietolin
    Guaietolin is an organic synthesis intermediate. Guaietolin is a marker of hypertension with significant reduced level in plasma metabolites. Guaietolin can be used for synthesis of sulfonamide esters with carbonic anhydrase inhibitory activity. Guaietolin can be used for glaucoma and hypertension research.
    Guaietolin
  • HY-134578
    H-Arg-Ser-Arg-OH
    H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound.
    H-Arg-Ser-Arg-OH
  • HY-78726A
    Fosamprenavir sodium
    Fosamprenavir sodium is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir sodium is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir sodium can be used for the study of human immunodeficiency virus (HIV-1) infection.
    Fosamprenavir sodium
  • HY-W007539R
    2,4-Dihydroxybenzaldehyde (Standard)
    2,4-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,4-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions.
    2,4-Dihydroxybenzaldehyde (Standard)
  • HY-Z0549
    (2,3-Dimethoxyphenyl)methanol
    (2,3-Dimethoxyphenyl)methanol is a drug impurity.
    (2,3-Dimethoxyphenyl)methanol
  • HY-W007692R
    Acetylpyrazine (Standard)
    Acetylpyrazine (Standard) is the analytical standard of Acetylpyrazine. This product is intended for research and analytical applications. Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds).
    Acetylpyrazine (Standard)
  • HY-134123
    Lipoxin B4 methyl ester
    Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4; Item No. 20110) and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.
    Lipoxin B4 methyl ester
  • HY-116161
    Bimatoprost isopropyl ester
    15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
    Bimatoprost isopropyl ester
  • HY-W010321
    Furfuryl acetate
    Furfuryl acetate can be used in the synthesis of 5-acetoxymethyl-2-vinylfuran and 5-hydroxymethyl-2-vinylfuran.
    Furfuryl acetate
  • HY-128753S6
    D-Lyxose-d
    D-Lyxose-d is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose.
    D-Lyxose-d
  • HY-174846
    TRPM8 antagonist 4 prodrug
    TRPM8 antagonist 4 prodrug (Compound 8b) is an orally active CB2R agonist (EC50: 51.2 nM) and a weak TRPM8 antagonist. TRPM8 antagonist 4 prodrug is a prodrug of TRPM8 antagonist 4 (HY-174825). TRPM8 antagonist 4 prodrug exhibits anti-inflammatory and analgesic activities and can be used in the research of inflammation-related pain disorders.
    TRPM8 antagonist 4 prodrug
  • HY-W013677S
    4-Fluorobenzoic acid-13C6
    4-Fluorobenzoic acid-13C6 is the 13C6 labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity.
    4-Fluorobenzoic acid-<sup>13</sup>C<sub>6</sub>
  • HY-78139R
    L-Xylose (Standard)
    L-Xylose (Standard) (L-(-)-Xylose (Standard)) is the analytical standard of L-Xylose (HY-78139). This product is intended for research and analytical applications. L-Xylose (L-(-)-Xylose) is a rare sugar and the levorotatory form of Xylose (HY-N0537). L-Xylose can be used as a raw material for the synthesis of various drugs and bioactive molecules.
    L-Xylose (Standard)
  • HY-131096
    L-Proline 4-methoxy-β-naphthylamide hydrochloride
    L-Proline 4-methoxy-β-naphthylamide hydrochloride (H-Pro-4MβNA hydrochloride) can be used for Fap-activated anti-tumor compounds preparaction.
    L-Proline 4-methoxy-β-naphthylamide hydrochloride
  • HY-W012956R
    2-Acetylpyrrole (Standard)
    2-Acetylpyrrole (Standard) is the analytical standard of 2-Acetylpyrrole. This product is intended for research and analytical applications. 2-Acetylpyrrole is a product of model browning systems, and has been isolated as a major flavour component of many foods[1]. 2-Acetylpyrrole has been used in the synthesis of 2-acetyl-1-pyrroline[2].
    2-Acetylpyrrole (Standard)
  • HY-100062
    2,4-Dibromo-5-nitropyridine
    2,4-Dibromo-5-nitropyridine is a trisubstituted pyridine derivative used to prepare Rho kinase inhibitors.
    2,4-Dibromo-5-nitropyridine
  • HY-B0191B
    Bimatoprost methyl ester
    Bimatoprost methyl ester is a proagent of Bimatoprost (HY-B0191).
    Bimatoprost methyl ester
  • HY-N6071R
    Secoisolariciresinol (Standard)
    Artemether (Standard) ((-)-Secoisolariciresinol (Standard)) is the analytical standard of Artemether (HY-N6071). This product is intended for research and analytical applications. Secoisolariciresinol ((-)-Secoisolariciresinol) is a plant lignan and a precursor of enterolignans. Secoisolariciresinol can be converted into enterodiol and enterolactone by intestinal microflora. Secoisolariciresinol may reduce the risk of cancer and cardiovascular diseases.
    Secoisolariciresinol (Standard)
  • HY-128383S
    1-Methylpyrrolidine-d8
    1-Methylpyrrolidine-d8 is the deuterium labeled 1-Methylpyrrolidine (HY-128383). 1-Methylpyrrolidine is a methylated pyrrolidine, which can be used as a precursor to synthesize polyfluorinated pyrrolidine derivatives.
    1-Methylpyrrolidine-d<sub>8</sub>
  • HY-W010255S
    Phenylglyoxylic acid-d5
    Phenylglyoxylic acid-d5 (Benzoylformic acid-d5) is a deuterium labeled Phenylglyoxylic acid (HY-W010255). Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds.
    Phenylglyoxylic acid-d<sub>5</sub>