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  4. Drug Intermediate

Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (2203):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-40421
    (R)-3-Fluoropyrrolidine hydrochloride
    		99.90%
    (R)-3-Fluoropyrrolidine hydrochloride is an intermediate. (R)-3-Fluoropyrrolidine hydrochloride can be used in the synthesis of hVanin-1 inhibitor (Compound X20). (R)-3-Fluoropyrrolidine hydrochloride can be used in the research of inflammatory bowel disease.
    (R)-3-Fluoropyrrolidine hydrochloride
  • HY-W015301S2
    Dimethyl adipate-d8
    		98.0%
    Dimethyl adipate-d8 (Hexanedioic acid dimethyl ester-d8) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.
    Dimethyl adipate-d<sub>8</sub>
  • HY-128994
    GGFG-Exatecan
    GGFG-Exatecan is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan can be used for the study of cancer.
    GGFG-Exatecan
  • HY-W007390
    Methyl 2-amino-5-bromobenzoate
    		98.89%
    Methyl 2-amino-5-bromobenzoate (Compound 8/12) is a biochemical reagent. Methyl 2-amino-5-bromobenzoate can be used to synthesize 2-benzamidobenzoic acid, a known FabH inhibitor. Derivatives of methyl 2-amino-5-bromobenzoate also inhibit PqsD, the pqs quorum sensing (QS) system, of Pseudomonas aeruginosa.
    Methyl 2-amino-5-bromobenzoate
  • HY-W008356
    2-Fluoro-4-iodobenzonitrile
    2-Fluoro-4-iodobenzonitrile is a building block, which can be used to synthesize L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors. 2-Fluoro-4-iodo benzonitrile can also be used to synthesize transient receptor potential ankyrin 1 (TRPA1) antagonists.
    2-Fluoro-4-iodobenzonitrile
  • HY-159162
    7-(2-Aminoethyl)camptothecin
    7-(2-Aminoethyl)camptothecin (7CPT) is a derivative of camptothecin that can be used to prepare TFO-CPT conjugates.
    7-(2-Aminoethyl)camptothecin
  • HY-W007712
    2-Bromo-3-methylpyridine
    		99.43%
    2-Bromo-3-methylpyridine (2-Bromo-3-picoline) is a heterocyclic intermediate of the halomethylpyridine family. 2-Bromo-3-methylpyridine can be used in the synthesis of platinum(IV) diazide complexes.
    2-Bromo-3-methylpyridine
  • HY-76030
    Nortropinone hydrochloride
    		≥98.0%
    Nortropinone hydrochloride is a derivative of Tropinone (HY-Y0135). Nortropinone hydrochloride is an important pharmaceutical intermediate for the synthesis of other active compounds.
    Nortropinone hydrochloride
  • HY-32833
    2-Chloro-3-pyridinol
    		99.92%
    2-Chloro-3-pyridinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Chloro-3-pyridinol can also be used in the synthesis of other active compounds. In addition, 2-Chloro-3-pyridinol is a halopyridinol disinfection by-product in drinking water samples.
    2-Chloro-3-pyridinol
  • HY-131092A
    H-Asn-Arg-OH diTFA
    		99.83%
    H-Asn-Arg-OH diTFA is a dipeptide formed by the connection of asparagine and arginine via a peptide bond, which can be used in polypeptide synthesis.
    H-Asn-Arg-OH diTFA
  • HY-W010174
    2-Chloro-4-nitropyridine
    		99.86%
    2-Chloro-4-nitropyridine is a drug intermediate in synthesizing other organic compounds, such as 2-chloro-4-ethoxypyridine and various RET kinase inhibitors.
    2-Chloro-4-nitropyridine
  • HY-W157376
    PAMAM Dendrimer G0.0 amine (20% in methanol)
    PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems.
    PAMAM Dendrimer G0.0 amine (20% in methanol)
  • HY-78139S1
    L-Xylose-2-13C
    		99.0%
    L-Xylose-2-13C ((L-(-)-Xylose-2-13C)) is the 13C labeled L-Xylose (HY-78139). L-Xylose (L-(-)-Xylose) is a rare sugar and the levorotatory form of Xylose (HY-N0537). L-Xylose can be used as a raw material for the synthesis of various drugs and bioactive molecules.
    L-Xylose-2-<sup>13</sup>C
  • HY-42121
    4-Bromo-2-fluoro-1-iodobenzene
    		99.98%
    4-Bromo-2-fluoro-1-iodobenzene is an intermediate. 4-Bromo-2-fluoro-1-iodobenzene can be used in the synthesis of Example 33. 4-Bromo-2-fluoro-1-iodobenzene can be used in lung adenocarcinoma research.
    4-Bromo-2-fluoro-1-iodobenzene
  • HY-145800
    Photocaged DAP TFA
    		99.86%
    Photocaged DAP (pm-DAP) TFA is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP TFA can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP TFA can be used as an intermediate to capture biosynthetic acylase.
    Photocaged DAP TFA
  • HY-133994
    Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin
    		99.73%
    Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is a perbrominated γ-cyclodextrin at the primary side. Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is also a commonly used intermediate in the modification of cyclodextrin.
    Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin
  • HY-N7130
    Thioisonicotinamide
    		99.82%
    Thioisonicotinamide (4-Pyridylthioamide) is a synthetic intermediate used for pharmaceutical synthesis.
    Thioisonicotinamide
  • HY-117289
    AKOS B018304
    		99.37%
    AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
    AKOS B018304
  • HY-153552
    NH2-UAMC1110
    NH2-UAMC1110 is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors.
    NH2-UAMC1110
  • HY-N2840
    Allitol
    		99.61%
    Allitol is a rare natural polyol that can be used as a sweetener. Allitol is a sugar alcohol formed by linking D- and L-hexoses in a process called izumoring. Allitol has anti-diabetic effects in a long-term allitol diet rat model. Allitol significantly increases the phylum Bacillota and decreases the phyla Bacteroidetes Actinomycetota, and Pseudomonadota. Allitol significantly increases the levels of butyric acid-metabolizing enzymes in a PICRUSt2 gut microbiota analysis. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS.
    Allitol