2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1385):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-106873
    Nepinalone
    Nepinalone, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity.
    Nepinalone
  • HY-137951
    Metizolam
    		99.30%
    Metizolam, a thienotriazolodiazepine, is the demethylated analogue of Etizolam. Metizolam exhibits psychomotor stabilizing, anxiolytic, sedative, myo-relaxant and amnestic effects.
    Metizolam
  • HY-W010062
    4-Chlorophenylacetic acid
    		99.93%
    4-Chlorophenylacetic acid is a halogenated phenylacetic acid derivative. 4-Chlorophenylacetic acid is a potent aromatase inhibitor and antagonizes estrogen signaling. 4-Chlorophenylacetic acid can provide carbon and energy for Pseudomonas sp. strain CBS3. 4-Chlorophenylacetic acid is effective against estrogen-induced mammary tumorigenesis.
    4-Chlorophenylacetic acid
  • HY-125847
    Salvianolic acid F
    		99.72%
    Salvianolic acid F is a kind of Salvianolic Acids. Salvianolic Acids is the most effective and abundant compounds extracted from Salvia miltiorrhiza, with good anti-oxidative activity.
    Salvianolic acid F
  • HY-164165
    Paclitaxel-2′-succinate NHS ester
    		98.78%
    Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy.
    Paclitaxel-2′-succinate NHS ester
  • HY-111013
    VK-II-86
    VK-II-86 is a Carvedilol (HY-B0006) analogue lacking antagonist activity at β-adrenoceptors, in hypokalaemia. VK-II-86 prevents hypokalaemia-induced ventricular arrhythmia through multi-channel effects. VK-II-86 prevents all hypokalaemia-induced changes in ion channel activity and oxidative stress.
    VK-II-86
  • HY-49070
    WAY-604440
    		≥98.0%
    WAY-604440 is an active molecule.
    WAY-604440
  • HY-32364
    3-arylisoquinolinamine derivative
    		99.10%
    3-arylisoquinolinamine derivative is a 3-arylisoquinolinamine derivative with antitumor activity.
    3-arylisoquinolinamine derivative
  • HY-108795B
    [Gly8]-GLP-1(7-37) acetate
    [Gly8]-GLP-1(7-37) acetate is a derivative of GLP-1 containing alanine-to-glycine substitution at positions 8. [Gly8]-GLP-1(7-37) acetate is also a peptide fragment of the GLP-1 receptor (GLP-1R) agonist Dulaglutide (HY-P0120).
    [Gly8]-GLP-1(7-37) acetate
  • HY-137994
    Deschloroetizolam
    		99.82%
    Deschloroetizolam is a designer Benzodiazepine. Deschloroetizolam is a psychoactive substance, with physical and cognitive effects.
    Deschloroetizolam
  • HY-B2208
    Glycol salicylate
    		98.83%
    Glycol salicylate is a derivative of salicylic acid that effectively moisturizes the stratum corneum and improves the aesthetic appearance of the skin.
    Glycol salicylate
  • HY-W793473
    WAY-301398
    WAY-301398 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-301398
  • HY-W014081
    Ethyl 3-coumarincarboxylate
    		99.81%
    Ethyl 3-coumarincarboxylate is a coumarin derivative. Ethyl 3-coumarincarboxylate can be used as a pseudo-template to give a molecularly imprinted polymer (MIP) that has a fairly specific recognition capability for aflatoxins.
    Ethyl 3-coumarincarboxylate
  • HY-121936A
    Yohimbic acid hydrate
    		99.96%
    Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA).
    Yohimbic acid hydrate
  • HY-136584
    2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid
    		≥98.0%
    2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid is a ketone compound extracted from patent WO2002030860A2, compound example II-9. 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid can be used for the research of cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders.
    2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid
  • HY-129801
    N-Ethyl Hexylone hydrochloride
    		≥99.0%
    N-Ethyl Hexylone hydrochloride is a synthetic Cathinone and analogue of methylone and other beta-keto methylenedioxyamphetamines.
    N-Ethyl Hexylone hydrochloride
  • HY-136647
    8-Bromoadenosine 5'-triphosphate tetrasodium
    8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is an ATP analogue. ATP is a central component of energy storage and metabolism in vivo.
    8-Bromoadenosine 5'-triphosphate tetrasodium
  • HY-130487
    miR-21-IN-2
    miR-21-IN-2 is an active compound.
    miR-21-IN-2
  • HY-N6654
    Syringyl Alcohol
    		98.16%
    Syringyl Alcohol (Syringic Alcohol) is a derivate of phenol comprises both phenolic and alcoholic functional groups. Syringyl Alcohol is a probe molecule for the evaluation of the catalytic performance of various carbonaceous nanomaterials (CNMs).
    Syringyl Alcohol
  • HY-W023983
    Chalcone dibromide
    Chalcone dibromide is a useful synthon in the synthesis of a large number of bioactive molecules such as pyrazolines, hydroxy pyrazolines, isoxazoles etc. Chalcone dibromide possesses antioxidant effects against tumor cells by inhibiting superoxide production and lipid peroxidation. Chalcone dibromide can be used for cancer disease research.
    Chalcone dibromide