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  4. Monomethyl itaconate

Monomethyl itaconate  (Synonyms: β-Methyl itaconate)

Cat. No.: HY-W094214 Purity: 99.45%
COA
SDS
Handling Instructions Technical Support

Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative of Itaconic acid (HY-Y0520). Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels.

For research use only. We do not sell to patients.

Monomethyl itaconate

Monomethyl itaconate Chemical Structure

CAS No. : 7338-27-4

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Monomethyl itaconate Related Antibodies

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Description

Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative of Itaconic acid (HY-Y0520). Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels[1].

Molecular Weight

144.13

Formula

C6H8O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=C(CC(OC)=O)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (693.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9382 mL 34.6909 mL 69.3818 mL
5 mM 1.3876 mL 6.9382 mL 13.8764 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.45%

COA (244 KB) HNMR (111 KB) GC (225 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.9382 mL 34.6909 mL 69.3818 mL 173.4545 mL
5 mM 1.3876 mL 6.9382 mL 13.8764 mL 34.6909 mL
10 mM 0.6938 mL 3.4691 mL 6.9382 mL 17.3455 mL
15 mM 0.4625 mL 2.3127 mL 4.6255 mL 11.5636 mL
20 mM 0.3469 mL 1.7345 mL 3.4691 mL 8.6727 mL
25 mM 0.2775 mL 1.3876 mL 2.7753 mL 6.9382 mL
30 mM 0.2313 mL 1.1564 mL 2.3127 mL 5.7818 mL
40 mM 0.1735 mL 0.8673 mL 1.7345 mL 4.3364 mL
50 mM 0.1388 mL 0.6938 mL 1.3876 mL 3.4691 mL
60 mM 0.1156 mL 0.5782 mL 1.1564 mL 2.8909 mL
80 mM 0.0867 mL 0.4336 mL 0.8673 mL 2.1682 mL
100 mM 0.0694 mL 0.3469 mL 0.6938 mL 1.7345 mL
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Monomethyl itaconate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monomethyl itaconate7338-27-4β-Methyl itaconateDrug DerivativeDrug derivativehydrogelsdrug deliveryInhibitorinhibitorinhibit

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