1. Signaling Pathways
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Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-120252
    ABC44
    Inhibitor 98.7%
    ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis.
    ABC44
  • HY-160610A
    Carbamoyl phosphate dilithium salt
    Carbamoyl phosphate dilithium salt is an antisickling agent and plays a significant role in the urea cycle. Carbamoyl phosphate dilithium salt carbamylates the amino-terminal valine residues of hemoglobin S in erythrocytes, which interferes with the sickling phenomenon. Carbamoyl phosphate dilithium salt exhibits toxicity due to the lithium cation.
    Carbamoyl phosphate dilithium salt
  • HY-147149
    BPN-15477
    Modulator 99.92%
    BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research.
    BPN-15477
  • HY-153074
    ISR-IN-1
    98.92%
    ISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM).
    ISR-IN-1
  • HY-155528
    O4I4
    98.73%
    O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research.
    O4I4
  • HY-170506
    KB-208
    98.00%
    KB-208 is a phagocytosis inhibitor that improves immune thrombocytopenia (ITP) in mouse models at a dose of 1 mg/kg. KB-208 does not affect other blood parameters and does not elevate serum toxicity biomarkers. KB-208 can be used in immunology research.
    KB-208
  • HY-17480
    Bendazac
    99.92%
    Bendazac is an oxyacetic acid with anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties. Bendazac acts by preventing protein denaturation and delays the cataractogenic process.
    Bendazac
  • HY-19720A
    Emixustat hydrochloride
    99.29%
    Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD).
    Emixustat hydrochloride
  • HY-B1170
    Cyclandelate
    98.66%
    Cyclandelate is a vasodilator that can be used in the study of claudication, arteriosclerosis, Raynaud's disease, nocturnal leg cramps, and migraines.
    Cyclandelate
  • HY-W777986
    1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine
    98.87%
    1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine (1-EPA-2-OH-sn-glycerol-3-phosphocholine) is an ester product.
    1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine
  • HY-B1032
    Dropropizine
    99.32%
    Dropropizine ((±)-Dropropizine; UCB-196) is an orally effective, peripherally selective antitussive that inhibits the activity of peripheral receptors and afferent nerves in the respiratory tract. Dropropizine acts on the cough reflex pathway, does not pass the blood-brain barrier, and has no central nervous system side effects. Dropropizine mainly regulates the level of sensory neuropeptides and inhibits the afferent signal transmission of the cough reflex, thereby alleviating the symptoms of dry cough, and has both mild local anesthetic and antihistamine activity. Dropropizine is mainly used for symptomatic research on dry cough caused by respiratory diseases.
    Dropropizine
  • HY-110329
    ML179
    Agonist 99.73%
    ML179 (SR-1309) is a inverse LRH1/NR5A2 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer.
    ML179
  • HY-Y1840
    3-Methoxyphenol
    98.91%
    3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
    3-Methoxyphenol
  • HY-112514
    1,3,6,8-Tetrahydroxynaphthalene
    98.35%
    1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin.
    1,3,6,8-Tetrahydroxynaphthalene
  • HY-W011165
    L-Lysyl-L-lysine dihydrochloride
    L-Lysyl-L-lysine (Lysyllysine) dihydrochloride is an enzyme cleavable basic amino acid. L-Lysyl-L-lysine dihydrochloride can be used for delivering multiple biologically active peptides.
    L-Lysyl-L-lysine dihydrochloride
  • HY-136808
    Pfn1-IN-1
    99.17%
    Pfn1-IN-1 (compound C1) is a Pfn1 inhibitor that inhibits the angiogenic capacity of endothelial cells (EC). Pfn1 is a regulator of the actin cytoskeleton, inducing actin polymerization and essential cellular activities. Pfn1-IN-1 inhibits Pfn1-Actin interaction and Actin polymerization.
    Pfn1-IN-1
  • HY-N3339
    Macrocarpal J
    Macrocarpal J, a phloroglucinol sesquiterpene-coupled compound, can be isolated from the leaves of Eucalyptus globulus.
    Macrocarpal J
  • HY-101701
    Hepronicate
    99.95%
    Hepronicate is a peripheral vasodilator with blood lipid lowering action.
    Hepronicate
  • HY-121872
    DP-b99
    Chemical
    DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.
    DP-b99
  • HY-46225
    DEX-maleimide
    99.80%
    DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases.
    DEX-maleimide
Cat. No. Product Name / Synonyms Application Reactivity