2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-139616
    Sec61-IN-2
    		Inhibitor 99.51%
    Sec61-IN-2 (A347) is a protein secretion inhibitor (extracted from patent WO2020176863).
    Sec61-IN-2
  • HY-153074
    ISR-IN-1
    ISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM).
    ISR-IN-1
  • HY-110329
    ML179
    		Agonist 99.73%
    ML179 (SR-1309) is a inverse LRH1/NR5A2 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer.
    ML179
  • HY-148508
    PhosTAC3
    		99.97%
    PhosTAC3 is a phosphorylation targeting chimera (PhosTAC) molecule composed of a linker with three PEG groups. PhosTAC3 induces dephosphorylation of PDCD4 and FOXO3a.
    PhosTAC3
  • HY-112514
    1,3,6,8-Tetrahydroxynaphthalene
    		98.35%
    1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin.
    1,3,6,8-Tetrahydroxynaphthalene
  • HY-160791A
    Claramine TFA
    Claramine TFA is a steroidal polyamine. Claramine TFA can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and toxins derived from biological proteins.
    Claramine TFA
  • HY-119443
    Neridronate
    		≥98.0%
    Neridronate is an aminobisphosphonate, licensed in Italy for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB). Neridronate is effective also in other skeletal diseases such as osteoporosis, algodystrophy, hypercalcemia of malignancy, and bone metastases.
    Neridronate
  • HY-17480
    Bendazac
    		99.92%
    Bendazac is an oxyacetic acid with anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties. Bendazac acts by preventing protein denaturation and delays the cataractogenic process.
    Bendazac
  • HY-148509
    PhosTAC5
    		98.02%
    PhosTAC5 is a phosphorylation targeting chimera (PhosTAC) molecule composed of a linker with fivePEG groups. PhosTAC5 induces dephosphorylation of PDCD4 and FOXO3a.
    PhosTAC5
  • HY-19720A
    Emixustat hydrochloride
    		99.29%
    Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD).
    Emixustat hydrochloride
  • HY-B1730
    Phensuximide
    		99.35%
    Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal.
    Phensuximide
  • HY-W010323
    2,5-Dihydroxy-1,4-benzoquinone
    		99.95%
    2,5-Dihydroxy-1,4-benzoquinone (DHBQ) is a organic ligand that can undergo a two-electron redox process per molecule.
    2,5-Dihydroxy-1,4-benzoquinone
  • HY-B1032
    Dropropizine
    		99.32%
    Dropropizine ((±)-Dropropizine; UCB-196) is an orally effective, peripherally selective antitussive that inhibits the activity of peripheral receptors and afferent nerves in the respiratory tract. Dropropizine acts on the cough reflex pathway, does not pass the blood-brain barrier, and has no central nervous system side effects. Dropropizine mainly regulates the level of sensory neuropeptides and inhibits the afferent signal transmission of the cough reflex, thereby alleviating the symptoms of dry cough, and has both mild local anesthetic and antihistamine activity. Dropropizine is mainly used for symptomatic research on dry cough caused by respiratory diseases.
    Dropropizine
  • HY-155528
    O4I4
    		98.73%
    O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research.
    O4I4
  • HY-126112
    Mephenoxalone
    		98.57%
    Mephenoxalone is a muscle relaxant with anti-anxiety activity. Mephenoxalone has neuropharmacologic activity in vivo. Mephenoxalone inhibits neuron transmission and can relax skeletal muscles by inhibiting the reflex arc.
    Mephenoxalone
  • HY-W011165
    L-Lysyl-L-lysine dihydrochloride
    		98.18%
    L-Lysyl-L-lysine (Lysyllysine) dihydrochloride is an enzyme cleavable basic amino acid. L-Lysyl-L-lysine dihydrochloride can be used for delivering multiple biologically active peptides.
    L-Lysyl-L-lysine dihydrochloride
  • HY-136808
    Pfn1-IN-1
    		99.17%
    Pfn1-IN-1 (compound C1) is a Pfn1 inhibitor that inhibits the angiogenic capacity of endothelial cells (EC). Pfn1 is a regulator of the actin cytoskeleton, inducing actin polymerization and essential cellular activities. Pfn1-IN-1 inhibits Pfn1-Actin interaction and Actin polymerization.
    Pfn1-IN-1
  • HY-12462
    WS3
    		98.70%
    WS3?is a novel proliferative molecule that promotes pancreatic β cell proliferation in rodent and human primary islets. WS3?can be used for the research of type 1 diabetes.
    WS3
  • HY-131062
    yGsy2p-IN-1
    		98.69%
    yGsy2p-IN-1 is a potent inhibitor for yeast glycogen synthase 2 (yGsy2p). yGsy2p-IN-1 is a competitive human glycogen synthase 1 (hGYS1) inhibitor with an IC50 of 2.75 μM and a Ki of 1.31 μM for wild-type hGYS1. yGsy2p-IN-H23 a pyrazole inhibitor, is used for glycogen storage diseases (GSDs).
    yGsy2p-IN-1
  • HY-147240
    Acloproxalap
    		99.92%
    Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes.
    Acloproxalap
Cat. No. Product Name / Synonyms Application Reactivity