2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-106844A
    (+)-EMD 57033
    		99.72%
    (+)-EMD 57033 is a cardiac troponin C (cTnC) activator, is a dominant Ca2+ sensitizer. (+)-EMD 57033 binds the cardiac/slow skeletal troponin C isoform and exerts myocardial contractile promotion function.
    (+)-EMD 57033
  • HY-120252
    ABC44
    		Inhibitor 98.7%
    ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis.
    ABC44
  • HY-163084
    HJ445A
    		98.31%
    HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research.
    HJ445A
  • HY-124366
    Slingshot inhibitor D3
    		99.46%
    Slingshot inhibitor D3 is a potent, selective, reversible and competitive inhibitor of Slingshot. The IC50 value for Slingshot 1 is 3 μM and the Ki value for Slingshot 2 is 3.9 μM. Slingshot inhibitor D3 has similar inhibitory activities toward both Slingshot 1 and Slingshot 2.
    Slingshot inhibitor D3
  • HY-W012145
    TMPD dihydrochloride
    		98.81%
    TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases. TMPD dihydrochloride is also a complex IV substrate.
    TMPD dihydrochloride
  • HY-14454
    TPh A
    		Inhibitor 99.81%
    TPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0.6 uM. TPh A disrupts the formation of the bcl3–pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells.
    TPh A
  • HY-19720A
    Emixustat hydrochloride
    		99.29%
    Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD).
    Emixustat hydrochloride
  • HY-B0932
    Levocarnitine propionate hydrochloride
    Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
    Levocarnitine propionate hydrochloride
  • HY-107343
    Docosahexaenoic acid ethyl ester
    Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects.
    Docosahexaenoic acid ethyl ester
  • HY-B1469
    Isosorbide
    		98.76%
    Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic.
    Isosorbide
  • HY-160523
    DBCO Ir catayst
    DBCO Ir catalyst is an iridium catalyst labeled with DBCO.
    DBCO Ir catayst
  • HY-112097
    E260
    		Inhibitor 99.05%
    E260 is a Fer/FerT kinase inhibitor.
    E260
  • HY-111652
    S-Gboxin
    		Inhibitor 99.62%
    S-Gboxin is a functional analog of the oxidative phosphorylation (OXPHOS) inhibitor Gboxin and has antitumor activity. S-Gboxin inhibits the growth of mouse and human glioblastoma with an IC50 of 470 nM. S-Gboxin has antitumor activity.
    S-Gboxin
  • HY-112431A
    Carnostatine hydrochloride
    		Inhibitor 99.81%
    Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent and selective carnosinase 1 (CN1) inhibitor with a Ki of 11 nM for human recombinant CN1. Carnostatine hydrochloride can be used for the treatment of diabetic nephropathy (DN).
    Carnostatine hydrochloride
  • HY-145551
    Atinvicitinib
    		98.03%
    Atinvicitinib is a kind of pyrazole compound. Atinvicitinib has the potential for the research of atopic dermatitis (extracted from patent WO2021123094A1).
    Atinvicitinib
  • HY-147149
    BPN-15477
    		Modulator 99.92%
    BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research.
    BPN-15477
  • HY-139616
    Sec61-IN-2
    		Inhibitor 99.51%
    Sec61-IN-2 (A347) is a protein secretion inhibitor (extracted from patent WO2020176863).
    Sec61-IN-2
  • HY-118090
    L-γ-Glutamyl-L-glutamic acid
    		99.72%
    L-γ-Glutamyl-L-glutamic acid (γ-Glu-Glu) is the isomer of D-γ-Glutamyl-D-glutamic acid (HY-118090A), and can be used as an experimental control. D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain.
    L-γ-Glutamyl-L-glutamic acid
  • HY-110329
    ML179
    		Agonist 99.83%
    ML179 (SR-1309) is a inverse LRH1/NR5A2 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer.
    ML179
  • HY-119443
    Neridronate
    		≥98.0%
    Neridronate is an aminobisphosphonate, licensed in Italy for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB). Neridronate is effective also in other skeletal diseases such as osteoporosis, algodystrophy, hypercalcemia of malignancy, and bone metastases.
    Neridronate
Cat. No. Product Name / Synonyms Application Reactivity