2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-117782
    Anticancer agent 236
    Anticancer agent 236 (compound JP-8g) is a broad-spectrum anticancer agent that has toxic effects on several cancer cell lines with IC50 values of 6.925 μM (MDA), 6.296 μM (U937), 6.548 μM (Jurkat), 6.373 μM (Hela), and 10.381 μM (EJ).
    Anticancer agent 236
  • HY-172604
    Neuroprotective agent 10
    Neuroprotective agent 10 (Compound 11c) is a brain-penetrant neuroprotective agent. Neuroprotective agent 10 scavenges ABTS radicals (scavenging IC50: 9.20 μM), DPPH radicals (scavenging IC50: 7.09 μM) and superoxide anion radicals (inhibition percentage: 48.4%). Neuroprotective agent 10 also alleviates H2O2-induced oxidative damage and LPS-induced neuroinflammation with antiepileptic activity. Neuroprotective agent 10 is promising for research of epilepsy and neuroprotection.
    Neuroprotective agent 10
  • HY-130272
    Anti-MI/R injury agent 1
    Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats.
    Anti-MI/R injury agent 1
  • HY-129450
    Ethyl-L-NIO hydrochloride
    		Inhibitor
    Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC50 of 70 μM and a Ki of 32 μM.
    Ethyl-L-NIO hydrochloride
  • HY-N1601
    2β,6β,15α-Trihydroxy-ent-kaur-16-ene
    2β,6β,15α-Trihydroxy-ent-kaur-16-ene (compound 19) is a compound isolated from the aerial parts of Pteris cretica.
    2β,6β,15α-Trihydroxy-ent-kaur-16-ene
  • HY-N15615
    Coromandaline
    Coromandaline is an alkaloid found in Heliotropium curassavicum.
    Coromandaline
  • HY-N1643
    2-[(1H-Indol-3-ylcarbonyl)amino]benzoic acid
    2-[(1H-Indol-3-ylcarbonyl)amino]benzoic acid (compound 8) is a compound isolated from the leaves of Baphicacanthus cusia.
    2-[(1H-Indol-3-ylcarbonyl)amino]benzoic acid
  • HY-P991592
    UB-221
    UB-221 is a humanized IgG1 monoclonal antibody inhibitor targeting IgE. UB-221 significantly decreases IgE synthesis by stabilization of membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated basophil activation and degranulation. UB-221 reduces IgE level in cynomolgus macaques and human IgE (ε, κ)-transgenic (hIGHE-knockin) mice. UB-221 can be used for asthma and chronic spontaneous urticaria (CSU) research.
    UB-221
  • HY-162411
    E3 ligase Ligand 24
    E3 ligase Ligand 24 (Compound 24) is a Potent Ligand for the E3 Ligase DCAF15 (IC50= 0.053 μM). Due to E3 ligase Ligand 24’s selectivity and potent binding characteristics, it is pivotal in the study of targeted protein degradation.
    E3 ligase Ligand 24
  • HY-148769
    Cefiderocol catechol 3-methoxy
    Cefiderocol catechol 3-methoxy is the metabolized product of cefiderocol (HY-17628) in the body.
    Cefiderocol catechol 3-methoxy
  • HY-149753
    Methylthiomcresol-succinaldehydic acid
    Methylthiomcresol-succinaldehydic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
    Methylthiomcresol-succinaldehydic acid
  • HY-156731
    (8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside
    (8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside (MDG) is a natural product isolated from Trachelospermum asiaticum.
    (8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside
  • HY-N1017
    11β-Hydroxycedrelone
    11β-Hydroxycedrelone is a natural tetranortriterpenoid compound isolated from the bark of Walsura yunnanensis.
    11β-Hydroxycedrelone
  • HY-161013
    Antiproliferative agent-44
    Antiproliferative agent-44 (compound 3) is a potent inhibitor of proliferation, with the IC50 values ranging from 2.02 to 1.61 μM.
    Antiproliferative agent-44
  • HY-113869
    BPH-628
    BPH-628 is an aromatic geranylgeranyl diphosphate synthase (GGPPS) inhibitor, with a pIC50 of 6.1.
    BPH-628
  • HY-118487A
    OB-24 free base
    OB-24 free base is a compound that potently and selectively inhibits heme oxygenase 1 (HO-1) and has the potential to inhibit advanced prostate cancer. OB-24 significantly reduces protein carbonylation and the formation of reactive oxygen species by selectively inhibiting HO-1 activity in prostate cancer cells. OB-24 significantly inhibited cell proliferation in vitro and inhibited tumor growth and lymph node and lung metastasis in vivo. OB-24 exhibits powerful synergy when used in combination with Taxol.
    OB-24 free base
  • HY-169164
    Antiproliferative agent-58
    Antiproliferative agent-58 (compound 8nj) is a potent antiproliferative agent. Antiproliferative agent-58 shows antiproliferative activity in normoxia and hypoxia.
    Antiproliferative agent-58
  • HY-115948
    Antitumor agent-46
    Antitumor agent-46 (Compound 2h) is an anti-tumor agent. Antitumor agent-46 demonstrates markedly higher antiproliferative activity on MCF-7 cells with an IC50 value of 2.08 µM.
    Antitumor agent-46
  • HY-N15630
    Pedicellin
    Pedicellin is a flavonoid compound that can be isolated from the medicinal plant Didymocarpus pedicellata.
    Pedicellin
  • HY-N10637
    N-Acetyldopamine dimer-1
    N-Acetyldopamine dimer-1 is a 2-(3',4'-dihydroxyphenyl)-1,4-benzodioxane derivative. N-Acetyldopamine dimer-1 is optically active, can be isolated from crude agent "Zentai," a cast-off shell of the cicada of Cryptotympana sp. (Cicadidae).
    N-Acetyldopamine dimer-1
Cat. No. Product Name / Synonyms Application Reactivity