2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B2172
    Vitamin K
    		98.70%
    Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.
    Vitamin K
  • HY-N6952
    Geraniol
    		≥98.0%
    Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes.
    Geraniol
  • HY-77956
    Thyminose
    		99.49%
    Thyminose is a natural product, a 2-deoxyaldopentose, that can be obtained by hydrolyzing the nucleosides that make up thym nucleic acid.
    Thyminose
  • HY-10448A
    Capsaicin (Purity 65%)
    		99.20%
    Capsaicin (Purity 65%) is a mixture of Capsaicin and Dihydrocapsaicin (Ratio >2:1). Capsaicin (Purity 65%) is an orally active capsaicin receptor (TRPV1) agonist.
    Capsaicin (Purity 65%)
  • HY-A0100
    Thiamine monochloride
    		99.96%
    Thiamine monochloride (Vitamin B1) is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.
    Thiamine monochloride
  • HY-B0722
    Histamine dihydrochloride
    		99.68%
    Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma.
    Histamine dihydrochloride
  • HY-121471
    Chrysoeriol
    		99.97%
    Chrysoeriol is a kind of natural yellow ash, which can be used for heating plants Coronopus didymus. Chrysoeriol suppresses the JAK2/STAT3, IκB/p65, and NF-κB pathways, and has strong anti-inflammatory activity.
    Chrysoeriol
  • HY-B0132
    Norfloxacin
    		98.31%
    Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
    Norfloxacin
  • HY-Y1088
    Hydrocinnamic acid
    		99.97%
    Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.
    Hydrocinnamic acid
  • HY-113524
    N-Acetyl-L-aspartic acid
    		99.45%
    N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease).
    N-Acetyl-L-aspartic acid
  • HY-A0126A
    Epoprostenol sodium
    		98.03%
    Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation.
    Epoprostenol sodium
  • HY-W010347S
    DL-Homocysteine-d4
    		98.4%
    DL-Homocysteine-d4 is the deuterium labeled DL-Homocysteine. DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain.
    DL-Homocysteine-d<sub>4</sub>
  • HY-107780B
    Cyclic-di-GMP diammonium
    		99.07%
    Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research.
    Cyclic-di-GMP diammonium
  • HY-N0067S
    γ-Aminobutyric acid-d6
    		99.92%
    γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors).
    γ-Aminobutyric acid-d<sub>6</sub>
  • HY-N0610
    Trans-Cinnamic acid
    		99.98%
    trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1.
    Trans-Cinnamic acid
  • HY-113038B
    α-Hydroxyglutaric acid
    		≥99.0%
    α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases.
    α-Hydroxyglutaric acid
  • HY-113131A
    Dihydroxyacetone phosphate hemimagnesium hydrate
    		99.90%
    Dihydroxyacetone phosphate hemimagnesium hydrate is an important intermediate in lipid biosynthesis and in glycolysis. It is a biochemical compound involved in many metabolic pathways, including the Calvin cycle in plants and glycolysis. Dihydroxyacetone phosphate hemimagnesium hydrate is found to be associated with transaldolase deficiency, which is an inborn error of metabolism.
    Dihydroxyacetone phosphate hemimagnesium hydrate
  • HY-N0814
    Phytic acid (50% in water)
    		99.31%
    Phytic acid (Inositol hexaphosphate) (50% in water) is a phosphorus storage compound of seeds and cereal grains. Phytic acid (50% in water) is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid (50% in water) inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
    Phytic acid (50% in water)
  • HY-124124
    N-Methylnicotinamide
    		99.72%
    N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. N-Methylnicotinamide is a potential biomarker in miR-1291-altered pancreatic cell metabolism and tumorigenesis.
    N-Methylnicotinamide
  • HY-N0474
    Tyrosol
    		99.93%
    Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
    Tyrosol
Cat. No. Product Name / Synonyms Application Reactivity