2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. MMP
  5. MMP Degrader

MMP Degrader

MMP Isoform Comparison

MMP Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-172777
    SDH-IN-25
    		Degrader
    SDH-IN-25 is a succinate dehydrogenase (SDH) inhibitor (IC50 = 4.82 mg/L). SDH-IN-25 exhibited broad-spectrum and potent antifungal activity. SDH-IN-25 mimics the interaction pattern of commercial fungicide Fluxapyroxad (HY-135549) through binding to SDH amino acid residues (TRP173, TYR58, and ARG43). SDH-IN-25 can induce hyphal morphology, interfere with respiratory metabolism by binding to complex II, generate reactive oxygen species (ROS), and affect mitochondrial membrane potential (MMP) in mycelia. SDH-IN-25 can be studied in research for agricultural disease control.