GHSR

GHSR Related Products (65):

By Effects:	Control (1) Inhibitors (3) Agonists (27) Antagonists (14) Activators (3) Inducer (1)

Cat. No.	Product Name	Effect	Purity

HY-14734

Anamorelin	Agonist	99.94%
Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia.

HY-50844

Ibutamoren Mesylate	Agonist	99.86%
Ibutamoren Mesylate (MK-677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. Ibutamoren Mesylate is an orally active growth hormone (GH) secretagogue.

HY-103007

TC-G-1008	Agonist	99.36%
TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC₅₀ values of 0.4 and 0.8 nM for rat and human receptors respectively.

HY-12584

PF-5190457	Inhibitor	98.21%
PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pK_i of 8.36.

HY-14734A

Anamorelin hydrochloride	Agonist	99.59%
Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia.

HY-P10964

Tezusomant	Antagonist
Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research of diseases such as acromegaly caused by excessive growth hormone secretion.

HY-108699

TM-N1324	Agonist	99.91%
TM-N1324 is an agonist of G-Protein-Coupled Receptor 39 (GPR39) with EC₅₀s of 9 nM/5 nM in the presence of Zn²⁺, and 280 nM/180 nM in the absence of Zn²⁺ for human/murine GPR39.

HY-13964A

YIL781 hydrochloride	Antagonist	99.48%
YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL781 hydrochloride inhibits the calcium response induced by ghrelin with pIC₅₀ values of 7.90 and 8.27, respectively.

HY-P1366

des-Gln14-Ghrelin		99.66%
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM.

HY-P3304

MR 409	Activator	99.51%
MR 409 is a selected growth hormone-releasing hormone (GHRH) agonist. MR 409 has remarkable neuroprotective effects through enhancing endogenous neurogenesis in cerebral ischemic mice. MR 409 also inhibits the in vivo growth of lung cancer.

HY-U00433

JMV 2959	Antagonist	99.91%
JMV 2959 is a growth hormone secretagogue receptor type 1a (GHS-R_1a) antagonist with an IC₅₀ of 32 nM.

HY-P0089A

Human growth hormone-releasing factor TFA		99.66%
Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.

HY-15243

Capromorelin Tartrate	Agonist	98.19%
Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with K_i of 7 nM for hGHS-R1a.

HY-P1155

GRF (1-29) amide (rat)	Inducer	99.94%
GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion.

HY-P0231

AZP-531		98.54%
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

HY-19884B

Relamorelin TFA	Agonist	99.81%
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a K_i of 0.42 nM for GHS-1a receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research.

HY-10957

L-692429	Agonist	99.90%
L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 binds to G protein-coupled receptor with a K_i of 63 nM.

HY-U00433A

JMV 2959 hydrochloride	Antagonist	98.20%
JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R_1a) antagonist with an IC₅₀ of 32±3 nM in LLC-PK₁ cells.

HY-P1421

Obestatin(human)	Inhibitor	99.52%
Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane.

HY-P10283

S1H	Antagonist	99.29%
S1H, a mimetic of hGH, is a human growth hormone receptor (hGHR) antagonist. S1H inhibits the interaction of hGH with hGHR. S1H inhibits phosphorylation of STAT5 in cells co-treated with hGH.

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