1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7102R
    Ceftiofur (Standard)
    Inhibitor
    Ceftiofur (Standard) is the analytical standard of Ceftiofur (HY-N7102). This product is intended for research and analytical applications. Ceftiofur is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.
    Ceftiofur (Standard)
  • HY-N14784
    Dechloromycorrhizin A
    Inhibitor
    Dechloromycorrhizin A is an antibiotic with weak activity against Gram-positive bacteria, yeasts and mildew, and strong nematocidal activity.
    Dechloromycorrhizin A
  • HY-B1864C
    Kasugamycin sulfate
    Inhibitor
    Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models.
    Kasugamycin sulfate
  • HY-N5199
    4"-Demethylgentamicin C2
    Inhibitor
    4"-Demethylgentamicin C2 has anti-Gram-positive and negative bacteria activity.
    4
  • HY-107825R
    Flavonol (Standard)
    Inhibitor
    Flavonol (Standard) is the analytical standard of Flavonol. This product is intended for research and analytical applications. Flavonol is a cholinesterase (ChE) inhibitor, with an IC50 value of 120 μM and a Ki value of 74 μM. Flavonol has antioxidant, free radical-scavenging, antibacterial properties, and immune modulation functions. Flavonol inhibits the PriA helicase of Staphylococcus aureus. Flavonol can suppress the production of NO in LPS-activated RAW 264.7 cells by inhibiting the expression of the iNOS enzyme. Flavonol shows protective and analgesic effects in mice through various neuronal pathways. Flavonol can be used in research related to tumors and atherosclerosis diseases.
    Flavonol (Standard)
  • HY-N14626
    Pelagiomicin C
    Pelagiomicin C has the activity against Gram-positive bacteria and Gram-negative bacteria.
    Pelagiomicin C
  • HY-B0105R
    Ketoconazole (Standard)
    Ketoconazole (Standard) is the analytical standard of Ketoconazole. This product is intended for research and analytical applications. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
    Ketoconazole (Standard)
  • HY-B0507R
    Sulfathiazole (Standard)
    Inhibitor
    Sulfathiazole (Standard) is the analytical standard of Sulfathiazole (HY-B0507). This product is intended for research and analytical applications. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish.
    Sulfathiazole (Standard)
  • HY-N14096
    Pyloricidin A1
    Inhibitor
    Pyloricidin A1 is an antibiotic against Helicobacter pylori found in Bacillus sp. HC-70. Pyloricidin A1 has strong anti-Helicobacter pylori activity. Pyloricidin A1 has no activity against other bacteria and yeast.
    Pyloricidin A1
  • HY-N3491
    Isodictamnine
    Inhibitor
    Isodictamnine is a phototoxic furoquinoline compound of the Turnipaceae family. Isodictamnine is phototoxic to certain bacteria and yeasts under long-wave UV light.
    Isodictamnine
  • HY-N14476
    Kigamicin B
    Inhibitor
    Kigamicin B shows activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs of 0.025-0.78 μg/mL.
    Kigamicin B
  • HY-W904855
    Apicidin D2
    Inhibitor
    Apicidin D2 (Compound 4), a fungal metabolite, is a Accessory gene regulator A (AgrA) quorum-sensing inhibitor. Apicidin D2 has anti-virulence activity. Apicidin D2 suppresses MRSA agr activation and shows potent inhibitory activities against all agr types in a nonbiocidal manner. Apicidin D2 can be used for MRSA infections research.
    Apicidin D2
  • HY-N14965
    5,10-Dihydrophencomycin methyl ester
    Inhibitor
    5,10-Dihydrophencomycin methyl ester has very weak activity against Escherichia coli and Bacillus subtilis.
    5,10-Dihydrophencomycin methyl ester
  • HY-N6711A
    epi-Equisetin
    Inhibitor
    epi-Equisetin, a secondary metabolite, has antibacterial activity.
    epi-Equisetin
  • HY-170688
    Antibacterial agent 119
    Inhibitor
    Antibacterial agent 119 (Compound 21 g) is an antibacterial candidate against Methicillin (HY-121544)-resistant Staphylococcus aureus (MICs less than 1 μg/mL against tested strains). Antibacterial agent 119 induces ROS production. Antibacterial agent 119 also acts on the bacterial cell membrane to cause membrane breakage. Antibacterial agent 119 exhibits potent antibacterial activity with low cytotoxicity, rapid bactericidal ability, and good in vivo antibacterial activity.
    Antibacterial agent 119
  • HY-N14884
    Mureidomycin E
    Inhibitor
    Mureidomycin E is an antibiotic with anti-Pseudomonas aeruginosa activity.
    Mureidomycin E
  • HY-120203
    DA 1131
    Inhibitor
    DA 1131 is an anionic Carbapenem antibiotic. DA 1131 has broad spectrum antibacterial activity for both gram-positive and gram-negative organisms. DA 1131 is resistant to degradation by various types of β-lactamases.
    DA 1131
  • HY-B1374S2
    Florfenicol-13C6
    Inhibitor
    Florfenicol-13C6 (SCH-25298-13C6) is 13C labeled Florfenicol. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions.
    Florfenicol-<sup>13</sup>C<sub>6</sub>
  • HY-17580R
    Fidaxomicin (Standard)
    Inhibitor
    Fidaxomicin (Standard) is the analytical standard of Fidaxomicin. This product is intended for research and analytical applications. Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research.
    Fidaxomicin (Standard)
  • HY-174389
    Antibacterial agent 283
    Inhibitor
    Antibacterial agent 283 (Compound 13) is an antimicrobial agent. Antibacterial agent 283 is active against both Gram-positive and Gram-negative bacteria, with potency comparable to the antibiotic Ampicillin (HY-B0522).
    Antibacterial agent 283
Cat. No. Product Name / Synonyms Application Reactivity