2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14464
    Pneumocandin A1
    		Inhibitor
    Pneumocandin A1 is a lipopeptide antibiotic. Pneumocandin A1 has a strong anti-Candida effect. Pneumocandin A1 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL.
    Pneumocandin A1
  • HY-N14259
    Kerriamycin C
    		Inhibitor
    Kerriamycin C has anti-Gram-positive bacterial effect and can inhibits Ai's ascites cancer.
    Kerriamycin C
  • HY-178493
    Anti-MRSA agent 37
    		Inhibitor
    Anti-MRSA agent 37 (Compound 5B) is an antibacterial agent against methicillin-resistant Staphylococcus aureus (MRSA) (MIC=0.25-0.5 μg/mL). Anti-MRSA agent 37 inhibits biofilm formation, disrupts cell wall integrit, attacks cell membrane and induces oxidative stress. Anti-MRSA agent 37 is promising for research of MRSA-related diseases such as skin infections.
    Anti-MRSA agent 37
  • HY-B1174A
    Bekanamycin sulfate
    		Inhibitor
    Bekanamycin (Kanamycin B) sulfate is a minor component of the kanamycin complex, an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus, with antibacterial activity.
    Bekanamycin sulfate
  • HY-160238
    Bacillibactin
    		Inhibitor
    Bacillibactin (Corynebactin) is a cyclic tricatecholate siderophore. Bacillibactin’s primary function is to facilitate bacterial iron acquisition by chelating iron ions (Fe3+) from the environment, thereby aiding bacterial survival under iron-limited conditions. Bacillibactin exhibits direct antimicrobial activity, such as inhibition of the growth of the producing bacteria Pseudomonas aeruginosa and Aeromonas veronae, as well as plant pathogens such as Pseudomonas syringae.Bacillibactin can be used in antibacterial and antifungal research.
    Bacillibactin
  • HY-N6807S
    Elemicin-d3
    		Inhibitor
    Elemicin-d3 is deuterated labeled Pemafibrate (HY-17618). Pemafibrate is a highly selective PPARα agonist, with an EC50 of 1 nM.
    Elemicin-d<sub>3</sub>
  • HY-153571
    Homo-BacPROTAC6
    		Inhibitor
    Homo-BacPROTAC6 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis.
    Homo-BacPROTAC6
  • HY-N8520
    Variculanol
    		Inhibitor
    Variculanol is an antimicrobial, anticancer and anti-HCV NS3/4A Protease agent which can be extracted from marine fungus Aspergillus versicolor.
    Variculanol
  • HY-N13301
    Aloe vera
    		Inhibitor
    Aloe vera is an herbal plant known for its anti-inflammatory, antibacterial, anticancer, antioxidant, heart-protective, and wound-healing properties. Aloe vera can be used in research for tumors, diabetes, bone diseases, and cardiovascular diseases.
    Aloe vera
  • HY-121349
    Aerothionin
    		Inhibitor
    Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs).
    Aerothionin
  • HY-N14316
    Hongoquercin B
    		Inhibitor
    Hongoquercin B is a sesquiterpene antibiotic. Hongoquercin B is only resistant to Vancomycin-resistant Enterococcus faecium at high concentrations.
    Hongoquercin B
  • HY-N2192R
    Swertianolin (Standard)
    		Inhibitor
    Swertianolin (Standard) is the analytical standard of Swertianolin (HY-N2192). This product is intended for research and analytical applications. Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis.
    Swertianolin (Standard)
  • HY-N14350
    2'''-Hydroxychlorothricin
    		Inhibitor
    Hydroxychlorothricin is an antibiotic of the chlorothricin group. Hydroxychlorothricin can be found in Streptomyces sp. K818. Hydroxychlorothricin has anti-tumor effect and can prolong the survival period of ICR mice inoculated with Ehrlich cancer cells.
    2'''-Hydroxychlorothricin
  • HY-N8470
    Steffimycin B
    Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC50=2.19 μM).
    Steffimycin B
  • HY-N5142S1
    α-Terpineol-d6
    		Inhibitor
    α-Terpineol-d6 is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation.
    α-Terpineol-d6
  • HY-N13075
    Mycoplanecin A
    		Inhibitor
    Mycoplanecin A is a cyclic peptide antibiotic. Mycoplanecin A has strong anti-mycobacterial, luteus, and Hypococcus activity. Mycoplanecin A also has moderate anti-Xanthomonas oryzae activity. Mycoplanecin A also has antibacterial effect on some strains of Actinomycetes.
    Mycoplanecin A
  • HY-161086
    Antibiofilm agent-4
    Antibiofilm agent-4 (compound 4p) is a LasR inhibitor. Antibiofilm agent-4 shows the best antibiofilm and anti-QS properties.
    Antibiofilm agent-4
  • HY-138023
    Leucomycin A4
    		Inhibitor
    Leucomycin A4 is a macrolide antibiotic that can be extracted from S. kitasatoensis. Leucomycin A4 inhibits a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 µg/ml, respectively).
    Leucomycin A4
  • HY-N15088
    Lunatoic acid B
    		Inhibitor
    Lunatoic acid B has anti-mould (partial) and bacterial (individual) effects.
    Lunatoic acid B
  • HY-126637
    Marasmic acid
    		Inhibitor
    Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
    Marasmic acid
Cat. No. Product Name / Synonyms Application Reactivity