1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13629S1
    Etoposide-13C,d3
    Inhibitor
    Etoposide-13C,d3 is the 13C- and deuterium labeled Etoposide. Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy.
    Etoposide-<sup>13</sup>C,d<sub>3</sub>
  • HY-19895
    DS-8587
    Inhibitor
    DS-8587 is a new fluoroquinolone with significant antibacterial activity. The MIC value of DS-8587 against clinically isolated amoxicillin-resistant Bacillus strains is superior to ciprofloxacin and levofloxacin. The antibacterial activity of DS-8587 is less affected by adeA/adeB/adeC or abeM efflux pumps, and has more advantages than ciprofloxacin. DS-8587 has a lower single-step mutation frequency than ciprofloxacin. DS-8587 may be an effective drug for inhibiting amoxicillin-resistant Bacillus infections.
    DS-8587
  • HY-P11091
    PA2-GNU7
    Inhibitor
    PA2-GNU7 is an antimicrobial peptide (AMP). PA2-GNU7 exhibits potent antimicrobial activity with minimal inhibitory concentration (MIC) against P. aeruginosa, E. coli, S. typhimurium, S. aureus, and C. albicans are 2 μM, 1 μM, 2 μM, 2 μM, and 8 μM, respectively. PA2-GNU7 rapidly and selectively kills Pseudomonas aeruginosa without affecting other commensal bacteria. PA2-GNU7 significantly improves survival of mice infected with P. aeruginosa. PA2-GNU7 can be used for the research and development of therapeutic agents against MDR Pseudomonas aeruginosa infections.
    PA2-GNU7
  • HY-P1768
    Urechistachykinin I
    Inhibitor
    Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect.
    Urechistachykinin I
  • HY-150002
    Antibacterial agent 115
    Inhibitor
    Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent.
    Antibacterial agent 115
  • HY-N0404R
    Sinigrin (Standard)
    Inhibitor
    Sinigrin (Standard) (Allyl-glucosinolate (Standard)) is the analytical standard of Sinigrin (HY-N0404). This product is intended for research and analytical applications. Sinigrin (Allyl-glucosinolate) is an orally active glucosinolate found in cruciferous plants. Sinigrin possesses multiple activities such as anti-cancer, antibacterial, antifungal, anti-inflammatory, antioxidant, and inhibition of fat synthesis. Sinigrin can be used in the research of tumors, inflammatory, and metabolic diseases.
    Sinigrin (Standard)
  • HY-W746582
    Norethindrone-d7
    Norethindrone-d7 (Norethisterone-d7) is the deuterium labeled Norethindrone (HY-B0554). Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
    Norethindrone-d<sub>7</sub>
  • HY-N2048R
    2,2':5',2''-Terthiophene (Standard)
    Inhibitor
    2,2':5',2''-Terthiophene (Standard) is the analytical standard of 2,2':5',2''-Terthiophene. This product is intended for research and analytical applications. 2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.
    2,2':5',2''-Terthiophene (Standard)
  • HY-161413
    Antibacterial agent 204
    Inhibitor
    Antibacterial agent 204 (Compd P2-56-3) possesses potentiated Rifampin (RIF) activity against Acinetobacter baumannii and Klebsiella pneumoniae. Antibacterial agent 204 (Compd P2-56-3) disrupts the outer membrane of A. baumannii. T.
    Antibacterial agent 204
  • HY-17460R
    Garenoxacin (Standard)
    Inhibitor
    Garenoxacin (Standard) is the analytical standard of Garenoxacin. This product is intended for research and analytical applications. Garenoxacin (BMS284756) is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms.
    Garenoxacin (Standard)
  • HY-P5484
    SMAP-18
    Inhibitor
    SMAP-18 is a biological active peptide. (SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.)
    SMAP-18
  • HY-136943
    K-41
    Inhibitor
    K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity.
    K-41
  • HY-P5663
    Bombinin H-BO1
    Inhibitor
    Bombinin H-BO1 is an antimicrobial peptide derived from toad Bombina orientalis skin secretions. Bombinin H-BO1 is active against Candida albicans, and the MIC value is 256 mg/L.
    Bombinin H-BO1
  • HY-N15655
    Ravenelin
    Inhibitor
    Ravenelin is a xanthone that can be isolated from the endophytic fungus Exserohilum rostratum. Ravenelin exhibits antiprotozoal and antibacterial activity. Ravenelin is active against gram-positive bacterial strains. Ravenelin can be studied for hit-to-lead development, especially for Chagas Disease.
    Ravenelin
  • HY-N0113R
    Hordenine (Standard)
    Inhibitor
    Hordenine (Standard) is the analytical standard of Hordenine. This product is intended for research and analytical applications. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.
    Hordenine (Standard)
  • HY-162171
    Antibacterial agent 179
    Inhibitor
    Antibacterial agent 179 (Compound 23) is a potent antibacterial agent, which effectively kills both Gram-negative and Gram-positive bacteria. Antibacterial agent 179 shows potent in vivo antibacterial efficacy in murine corneal infection models caused by Staphylococcus aureus or Pseudomonas aeruginosa.
    Antibacterial agent 179
  • HY-14881B
    (Rac)-Bedaquiline
    Control
    (Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis.
    (Rac)-Bedaquiline
  • HY-N8148
    Cassiaside B
    Inhibitor
    Cassiaside B, a naphthopyrone, has potent antimicrobial activity.
    Cassiaside B
  • HY-B0113S1
    Omeprazole-d3-1
    Inhibitor
    Omeprazole-d3-1 is the deuterium labeled Omeprazole. Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
    Omeprazole-d<sub>3</sub>-1
  • HY-161028
    Antibacterial agent 167
    Inhibitor
    Antibacterial agent 167 (compound 13) is an inhibitor of pathogenic bacterial carbonic anhydrases. Antibacterial agent 167 inhibits the growth of N. gonorrhea strains at concentrations ranging from 16 to 64 µg/mL.
    Antibacterial agent 167
Cat. No. Product Name / Synonyms Application Reactivity