1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0017R
    Bergenin (Standard)
    Inhibitor
    Bergenin (Standard) is the analytical standard of Bergenin. This product is intended for research and analytical applications. Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties.
    Bergenin (Standard)
  • HY-106526
    Xibornol
    Inhibitor
    Xibornol (Bactacine) has strong antibacterial action against Streptococcus pneumoniae, Streptococcus pyogenes, and Staphyloccus aureus, as well as against Actinomyces israelii and Corynebacterium ulcerans. Xibornol has the potential for using for the antisepsis of the oral cavity and as adjuvant in pharyngeal infections caused by Gram-positive microorganisms.
    Xibornol
  • HY-P3916
    GVLSNVIGYLKKLGTGALNAVLKQ
    Inhibitor
    GVLSNVIGYLKKLGTGALNAVLKQ is an antimicrobial peptide with 24-amino acid. GVLSNVIGYLKKLGTGALNAVLKQ can potentially form α-helix. GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) has activity against Gram-negative, Gram-positive bacteria and the yeast Candida albicans.
    GVLSNVIGYLKKLGTGALNAVLKQ
  • HY-P5633
    Bombinin-like peptide 2
    Inhibitor
    Bombinin-like peptide 2 is an antimicrobial peptide derived from skin secretions of asian toad Bombina orientalis.
    Bombinin-like peptide 2
  • HY-162430
    Antibacterial agent 206
    Inhibitor
    Antibacterial agent 206 (Compound 10e) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-1 μg/mL. Antibacterial agent 206 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 206 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication.
    Antibacterial agent 206
  • HY-P5689
    Maximin 42
    Inhibitor
    Maximin 42 is an antimicrobial peptide. Maximin 42 has antibacterial activity against S. aureus (MIC: 37.5 μg/mL). Maximin 42 has hemolytic activities against human red cells.
    Maximin 42
  • HY-B0693A
    Ranitidine bismuth citrate
    Inhibitor
    Ranitidine bismuth citrate is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine bismuth citrate antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine bismuth citrate has selectivity for SARS-CoV-2-infected cells. Ranitidine bismuth citrate also has anti-Helicobacter pylori infection. Ranitidine bismuth citrate inhibits breast tumor development and spread in mice.
    Ranitidine bismuth citrate
  • HY-P2073
    Cyclo(δ-Ala-L-Val)
    Cyclo(Δ-Ala-L-Val) is a cyclic dipeptide and a putative quinolone signal (QS) molecule produced by Pseudomonas aeruginosa.
    Cyclo(δ-Ala-L-Val)
  • HY-155715
    G43
    Inhibitor 99.76%
    G43 is a potent, selective glucosyltransferase inhibitor, with the Kd of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo, and can be used for dental caries study.
    G43
  • HY-W039454R
    2,4-Dichlorobenzyl alcohol (Standard)
    Inhibitor
    2,4-Dichlorobenzyl alcohol (Standard) is the analytical standard of 2,4-Dichlorobenzyl alcohol (HY-W039454). This product is intended for research and analytical applications. 2,4-Dichlorobenzyl alcohol is an orally active mild antiseptic, with a broad spectrum for bacterial and virus associated with mouth and throat infections. 2,4-Dichlorobenzyl alcohol exhibits prenatal developmental toxicity.2,4-Dichlorobenzyl alcohol can be used in the study of SARS-CoV.
    2,4-Dichlorobenzyl alcohol (Standard)
  • HY-P10362
    Temporin-GHd
    Inhibitor
    Temporin-GHd exhibits antibacterial activity against Streptococcus mutans (MIC=13.1 μM; MBC=26 μM). Temporin-GHd increases the permeability of the bacterial cell membrane, causing membrane damage and leakage of cellular contents. Temporin-GHd disrupts preformed biofilms at high concentrations. Temporin-GHd can bind to bacterial DNA, inhibiting DNA migration.
    Temporin-GHd
  • HY-N1394S1
    p-Anisic acid-d4
    p-Anisic acid-d4 is the deuterium labeled p-Anisic acid. p-Anisic acid (4-Methoxybenzoic acid) is one of the isomers of anisic acid, with anti-bacterial and antiseptic properties.
    p-Anisic acid-d<sub>4</sub>
  • HY-N12264
    Burnettramic acid A
    Inhibitor
    Burnettramic acid A is an antibiotic, which can be isolated from Aspergillus burnettii. Burnettramic acid A exhibits antibacterial and antifungal activities, with IC50 of 0.2, 0.5, 2.3 and 5.9 μg/mL, for Saccharomyces cerevisiae, Candida albicans, Bacillus subtilis and Staphylococcus aureus, respectively. Burnettramic acid A exhibits cytotoxicity in cancer cell NS-1 with IC50 of 13.8 μg/mL.
    Burnettramic acid A
  • HY-178347
    Debio 1453
    Inhibitor
    Debio 1453 is a bactericidal FabI inhibitor potent against N. gonorrhoeae (IC50 = 0.6 nM), including drug-resistant strains. Debio 1453 demonstrates a low propensity for resistance selection and is effective in eradicating both planktonic and intracellular bacteria through a mechanism of concurrently inhibiting FabI and engaging the non-mutable NADH cofactor. Debio 1453 clears antibiotic-resistant N. gonorrhoeae infection in a murine vaginal model. Debio 1453 can be used for gonorrhoea research.
    Debio 1453
  • HY-B1599R
    Chloramphenicol palmitate (Standard)
    Inhibitor
    Chloramphenicol palmitate (Standard) is the analytical standard of Chloramphenicol palmitate (HY-B1599). This product is intended for research and analytical applications. Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol (HY-B0239), obtained from the esterification reaction between the agent and Palmitic acid (HY-N0830). Chloramphenicol palmitate is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol. Chloramphenicol is an orally effective broad-spectrum antibiotic.
    Chloramphenicol palmitate (Standard)
  • HY-162595
    BDM88855
    Inhibitor
    BDM88855 is an allosteric inhibitor for the homolog AcrB protein. BDM88855 can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli.
    BDM88855
  • HY-P2124R
    Cyclo(L-Trp-L-Trp) (Standard)
    Inhibitor
    L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro.
    Cyclo(L-Trp-L-Trp) (Standard)
  • HY-123286
    (E)-Triandrin
    Inhibitor
    (E)-Triandrin (Sachaliside 1) is a phenylpropanol glycoside, can be isolated from the bark of Populus Sakhalinensis. (E)-Triandrin exhibits cytotoxic activity against Artemia and human lung cancer cell line (H1299).
    (E)-Triandrin
  • HY-W083373
    (E)-3,4-Dimethoxychalcone
    Inhibitor
    (E)-3,4-Dimethoxychalcone is an isoform of 3,4-Dimethoxychalcone (HY-W083373A), a potential antimicrobial and antioxidant agent.
    (E)-3,4-Dimethoxychalcone
  • HY-14879BR
    Avibactam sodium hydrate (Standard)
    Inhibitor
    Avibactam (sodium hydrate) (Standard) is the analytical standard of Avibactam (sodium hydrate). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1].
    Avibactam sodium hydrate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity