2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-113756AR
    Latanoprost acid (Standard) 41639-83-2
    Latanoprost acid (Standard) is the analytical standard of Latanoprost acid. This product is intended for research and analytical applications. Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes.
    Latanoprost acid (Standard)
  • HY-118861S1
    Enclomiphene-d4 99.85%
    Enclomiphene-d4 ((E)-Clomiphene-d4) is a deuterium labeled Enclomiphene. Enclomiphen?is a potent and orally active?estrogen receptor?antagonist with antioestrogenic property.
    Enclomiphene-d4
  • HY-119674AR
    Xanthopterin hydrate (Standard) 5979-01-1 98%
    Xanthopterin (hydrate) (Standard) is the analytical standard of Xanthopterin (hydrate). This product is intended for research and analytical applications. Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat. Xanthopterin hydrate inhibits RNA synthesis.
    Xanthopterin hydrate (Standard)
  • HY-119695AR
    Simvastatin acid ammonium (Standard) 139893-43-9
    Simvastatin acid (ammonium) (Standard) is the analytical standard of Simvastatin acid (ammonium). This product is intended for research and analytical applications. Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
    Simvastatin acid ammonium (Standard)
  • HY-121467S1
    Acotiamide-d4 98%
    Acotiamide-d4 (Z-338 (free base)-d4) is deuterium labeled Acotiamide. Acotiamide is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with an IC50 of 1.79 μM. Acotiamide can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory.
    Acotiamide-d4
  • HY-124356AS
    Alcaftadine carboxylic acid-d3 sodium 98%
    Alcaftadine carboxylic acid-d3 (sodium) is deuterium labeled Alcaftadine carboxylic acid. Alcaftadine carboxylic acid is a broad-spectrum antihistamine compound with high affinity for histamine H1 and H2 receptors and low affinity for H4 receptors. Alcaftadine carboxylic acid has also demonstrated effects on modulating immune cell recruitment and stabilizing mast cells. Alcaftadine carboxylic acid is more effective than placebo in preventing ocular itching associated with allergic conjunctivitis and is at least as effective as olopatadine 0.01%.
    Alcaftadine carboxylic acid-d3 sodium
  • HY-125527AS
    17(R)-Resolvin D1-d5 98%
    17(R)-Resolvin D1-d5 (17(R)-RvD1-d5) is deuterium labeled 17(R)-Resolvin D1. 17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells. 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy.
    17(R)-Resolvin D1-d5
  • HY-126042S4
    (±)-Lisofylline-d4 1185879-05-3 98%
    (±)-Lisofylline-d4 ((±)-Lisophylline-d4) is deuterium labeled (±)-Lisofylline. (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research.
    (±)-Lisofylline-d4
  • HY-135731AR
    4-Methylamino antipyrine hydrochloride (Standard) 856307-27-2
    4-Methylamino antipyrine (hydrochloride) (Standard) is the analytical standard of 4-Methylamino antipyrine (hydrochloride). This product is intended for research and analytical applications. 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties.
    4-Methylamino antipyrine hydrochloride (Standard)
  • HY-138687S1
    Nirmatrelvir-d6 2861202-75-5 98%
    Nirmatrelvir-d6 (PF-07321332-d6) is deuterium labeled Nirmatrelvir. Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research.
    Nirmatrelvir-d6
  • HY-A0132S14
    N-Acetyl-D-glucosamine-d3 77369-11-0 98%
    N-Acetyl-D-glucosamine-d3 (N-Acetyl-2-amino-2-deoxy-D-glucose-d3) is deuterium labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits.
    N-Acetyl-D-glucosamine-d3
  • HY-B0656AS3
    Rabeprazole-13C,d3 sodium 98%
    Rabeprazole-13C,d3 (sodium) (LY307640-13C,d3 (sodium)) is 13C labeled Rabeprazole (sodium). Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-13C,d3 sodium
  • HY-B1490AS3
    Imipramine-d4-1 773801-61-9 98%
    Imipramine-d4-1 is the deuterium labeled Imipramine (HY-W010179). Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects.
    Imipramine-d4-1
  • HY-D0205AS1
    Carbocisteine-13C3-1 1391068-19-1 98%
    Carbocisteine-13C3-1 (Carbocysteine-13C3-1) is 13C labeled Carbocisteine. Carbocisteine is an orally active mucolytic agent. Carbocisteine attenuates the phosphorylation of NF-κB p65 and ERK1/2. Carbocisteine modulates Nrf2/HO-1 and NFκB interplay. Carbocisteine inhibits Apoptosis. Carbocisteine is used in chronic obstructive pulmonary disease (COPD) research.
    Carbocisteine-13C3-1
  • HY-D0205AS2
    Carbocisteine-d3 98%
    Carbocisteine-d3 (Carbocysteine-d3) is deuterium labeled Carbocisteine. Carbocisteine is an orally active mucolytic agent. Carbocisteine attenuates the phosphorylation of NF-κB p65 and ERK1/2. Carbocisteine modulates Nrf2/HO-1 and NFκB interplay. Carbocisteine inhibits Apoptosis. Carbocisteine is used in chronic obstructive pulmonary disease (COPD) research.
    Carbocisteine-d3
  • HY-W001174R
    2,5-Dihydroxyacetophenone (Standard) 490-78-8
    2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways.
    2,5-Dihydroxyacetophenone (Standard)
  • HY-W002116R
    Methyl syringate (Standard) 884-35-5
    Methyl syringate is a selective TRPA1 agonist. Methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway. Methyl syringate is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a chemical marker of Asphodel monofloral honey. Methyl syringate contributes to the antibacterial activity of honey. Methyl syringate inhibits aflatoxin production. Methyl syringate can contribute to weight suppression. Methyl syringate can be studies for cancer prevention (e.g. lung cancer), suppression of hypoxia-induced inflammatory response and tumorigenesis.
    Methyl syringate (Standard)
  • HY-W002438R
    6-Hydroxyindole (Standard) 2380-86-1
    6-Hydroxyindole (Standard) is the analytical standard of 6-Hydroxyindole. This product is intended for research and analytical applications. 6-Hydroxyindole is a biochemical reagent. 6-hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor, and is elevated plasma of the renal failure patients.
    6-Hydroxyindole (Standard)
  • HY-W004294R
    1-Tetradecanol (Standard) 112-72-1
    1-Tetradecanol (Standard) is the analytical standard of 1-Tetradecanol. This product is intended for research and analytical applications. 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity.
    1-Tetradecanol (Standard)
  • HY-W004295R
    1-Pentadecanol (Standard) 629-76-5
    1-Pentadecanol (Standard) is the analytical standard of 1-Pentadecanol. This product is intended for research and analytical applications. 1-Pentadecanol is a long-chain fatty alcohol. 1-Pentadecanol has anti-comedone activity. 1-Pentadecanol has moisturizing and hydrating properties and can be applied to skin care products. 1-Pentadecanol can be used in the production of surfactants, emulsifiers and lubricants.
    1-Pentadecanol (Standard)
Cat. No. Product Name / Synonyms Application Reactivity