2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

PDF 93.1 MB

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-106579R
    Tiaprofenic acid (Standard) 33005-95-7
    Tiaprofenic acid (Standard) is the analytical standard of Tiaprofenic acid. This product is intended for research and analytical applications. Tiaprofenic acid is an orally active nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory and analgesic potency. Tiaprofenic acid inhibits prostaglandin synthesis by suppressing cyclo-oxygenase (COX). Tiaprofenic acid can be used in the treatment of rheumatic diseases.
    Tiaprofenic acid (Standard)
  • HY-106628R
    Sudoxicam (Standard) 34042-85-8 98%
    Sudoxicam (Standard) is the analytical standard of Sudoxicam. This product is intended for research and analytical applications. Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity.
    Sudoxicam (Standard)
  • HY-106638R
    Voclosporin (Standard) 515814-01-4 98%
    Voclosporin (Standard) is the analytical standard of Voclosporin. This product is intended for research and analytical applications. Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor.
    Voclosporin (Standard)
  • HY-106638S
    Voclosporin-d4 98%
    Voclosporin-d4 (ISAtx-247-d4) is deuterium labeled Voclosporin. Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor.
    Voclosporin-d4
  • HY-106673R
    Hydrocortisone buteprate (Standard) 72590-77-3
    Hydrocortisone buteprate (Standard) is the analytical standard of Hydrocortisone buteprate. This product is intended for research and analytical applications. Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation.
    Hydrocortisone buteprate (Standard)
  • HY-106690R
    Centhaquin (Standard) 57961-90-7 98%
    Centhaquin (Standard) is the analytical standard of Centhaquin. This product is intended for research and analytical applications. Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce systemic vascular resistance in haemorrhagic models.
    Centhaquin (Standard)
  • HY-106714R
    Clocortolone pivalate (Standard) 34097-16-0
    Clocortolone pivalate (Standard) is the analytical standard of Clocortolone pivalate. This product is intended for research and analytical applications. Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis.
    Clocortolone pivalate (Standard)
  • HY-106924A
    Antiallergic agent-3 160665-99-6 98%
    Antiallergic agent-3 is a derivative of 2-(benzimidazol-2-yl)-1,3-diaminopropane with antiallergic activity.
    Antiallergic agent-3
  • HY-107015A
    Prednisolone metazoate sodium 630-67-1 98%
    Prednisolone metazoate sodium (ATL 2502) can be used for study of inflammatory bowel disease, ulcerative colitis, and GI disorders.
    Prednisolone metazoate sodium
  • HY-107033R
    Tetroxoprim (Standard) 53808-87-0
    Tetroxoprim (Standard) is the analytical standard of Tetroxoprim. This product is intended for research and analytical applications. Tetroxoprim is an antimicrobial DHFR inhibitor.
    Tetroxoprim (Standard)
  • HY-107072A
    Trantinterol hydrochloride 611234-02-7 98%
    Trantinterol hydrochloride is an orally active β2-adrenergic Receptor agonist. Trantinterol hydrochloride can be used in the study of asthma.
    Trantinterol hydrochloride
  • HY-107203S
    Propentofylline-d6 1216516-37-8 98%
    Propentofylline-d6 (HWA 285-d6) is the deuterium labeled Propentofylline. Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia.
    Propentofylline-d6
  • HY-107378R
    L-Valyl-L-phenylalanine (Standard) 3918-92-1
    L-Valyl-L-phenylalanine (Standard) is the analytical standard of L-Valyl-L-phenylalanine. This product is intended for research and analytical applications. L-Valyl-L-phenylalanine (Valylphenylalanine; H-VAL-PHE-OH) has been reported as biocompatible polymer.
    L-Valyl-L-phenylalanine (Standard)
  • HY-107429R
    Abrocitinib (Standard) 1622902-68-4
    Abrocitinib (Standard) is the analytical standard of Abrocitinib. This product is intended for research and analytical applications. Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.
    Abrocitinib (Standard)
  • HY-107495R
    Betahistine EP Impurity C (Standard) 5452-87-9
    Betahistine EP Impurity C (Standard) is the analytical standard of Betahistine EP Impurity C. This product is intended for research and analytical applications. Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA).
    Betahistine EP Impurity C (Standard)
  • HY-107512R
    Kynurenic acid sodium (Standard) 2439-02-3
    Kynurenic acid (sodium) (Standard) is the analytical standard of Kynurenic acid (sodium). This product is intended for research and analytical applications. Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8.
    Kynurenic acid sodium (Standard)
  • HY-107569R
    Garcinol (Standard) 78824-30-3
    Garcinol (Standard) is the analytical standard of Garcinol. This product is intended for research and analytical applications. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively. Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity.
    Garcinol (Standard)
  • HY-107613R
    R 59-022 (Standard) 93076-89-2
    R 59-022 (Standard) is the analytical standard of R 59-022. This product is intended for research and analytical applications. R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils.
    R 59-022 (Standard)
  • HY-107632G
    GYY4137 (GMP) 106740-09-4 98%
    GYY4137 (GMP) is the GMP-grade version of GYY4137 (HY-107632). Small molecules of GMP grade can be used as adjuvant reagents in cell therapy. GYY4137 (GMP) is a sustained-release H2S donor possessing vasodilatory, antihypertensive, and anti-inflammatory activities. GYY4137 (GMP) can inhibit cell growth, induce apoptosis, and cause cell cycle arrest by blocking the STAT3 pathway, demonstrating potent anticancer activity.
    GYY4137 (GMP)
  • HY-107690R
    DMPO (Standard) 3317-61-1
    DMPO (Standard) is the analytical standard of DMPO. This product is intended for research and analytical applications. DMPO is a cell permeable hydrophillic spin trap agent for superoxide detection.
    DMPO (Standard)
Cat. No. Product Name / Synonyms Application Reactivity