2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1387
    Sulfamethoxypyridazine 80-35-3 99.67%
    Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic, for treatment of Dermatitis herpetiformis.
    Sulfamethoxypyridazine
  • HY-B2015
    Carbosulfan 55285-14-8 ≥98.0%
    Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers).
    Carbosulfan
  • HY-D0179
    Cyclam 295-37-4 ≥98.0%
    Cyclam is a metal chelator that forms metal complexes with a variety of metal ions. Cyclam metal complexes exhibits anti-HIV (such as AMD3100), nitric oxide (NO) releasing and scavenging (such as Zn(II)-Cyclam and Ru(II)-Cyclam), and SOD mimetic (such as Mn(III)-Cyclam and Zn(II)-Cyclam) activities.
    Cyclam
  • HY-N1103
    Vasicine 6159-55-3 ≥98.0%
    Vasicine (peganine) is a quinazoline alkaloid isolated from Justicia adhatoda. Vasicine activates PI3K/Akt signaling pathway, exhibits antioxidant, anti-inflammatory and antibacterial activities.
    Vasicine
  • HY-N8722
    Datiscetin 480-15-9 99.91%
    Datiscetin (compound 5) is a natural compound isolated from the cultivar “Roland”, and shows fungitoxic activity towards F. oxysporum f. sp. dianthi..
    Datiscetin
  • HY-Y1777
    2-Phenylacetophenone 451-40-1 99.96%
    2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization.
    2-Phenylacetophenone
  • HY-113784
    Thiocarlide 910-86-1 ≥99.0%
    Thiocarlide is a potent antibacterial agent. Thiocarlide inhibits Mycobacterium tuberculosis H37Rv, Mycobacterium bovisBCG, Mycobacterium avium, and Mycobacterium aurum A+ with MICs of 2.5, 0.5, 2.0 and 2.0 μg/mL, respectively.
    Thiocarlide
  • HY-114591
    Spiromesifen 283594-90-1
    Spiromesifen (BSN 2060) is a broad-spectrum tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase, and has no cross-resistance to any resistant mite or whitefly populations.
    Spiromesifen
  • HY-119904
    Malaoxon 1634-78-2 ≥98.0%
    Malaoxon is a pesticide metabolite. Malaoxon can induce cellular death in cultured human pulmonary cells. Malaoxon can be used for the research of pulmonary toxicity.
    Malaoxon
  • HY-133825
    Cyazofamid 120116-88-3 98.15%
    Cyazofamid exerts its bactericidal effect by impairing ATP production. Cyazofamid inhibits organic cation transporter 3 (OCT3) and OAT1, with IC50 values ​​of 1.54 and 17.3 μM, respectively.
    Cyazofamid
  • HY-157570
    Anti-inflammatory agent 70 2767427-87-0
    Anti-inflammatory agent 70 (N-Me-SP23) is a STING protein PROTAC degrader and inhibits the STING signaling pathway. Anti-inflammatory agent 70 has anti-inflammatory activity. (Pink: STING inhibitor (HY-47709); Black: linker (HY-W008296); Blue: CRBN Ligand (HY-W460193)).
    Anti-inflammatory agent 70
  • HY-15781A
    (R)-Morinidazole 898230-59-6 ≥98.0%
    (R)-Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N+-glucuronidation and sulfation. (R)-Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria.
    (R)-Morinidazole
  • HY-160519
    Targocil-II 955918-74-8 98.92%
    Targocil-II (Compound 2) is an ABC transporter inhibitor with a IC50 value of 137 nM. Targocil-II prevents ATP hydrolysis by binding to allosteric sites of the TM domain. Targocil-II has (antibacterial) activity.
    Targocil-II
  • HY-18062S
    Pyrimethamine-d3 1189936-99-9 99.90%
    Pyrimethamine-d3 is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).
    Pyrimethamine-d3
  • HY-B0105A
    (+)-Ketoconazole 142128-59-4 99.79%
    (+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
    (+)-Ketoconazole
  • HY-B0417A
    Lincomycin hydrochloride 859-18-7
    Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var.
    Lincomycin hydrochloride
  • HY-B0937A
    Amprolium hydrochloride 137-88-2 98.79%
    Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption.
    Amprolium hydrochloride
  • HY-B1596A
    Ceftizoxime sodium 68401-82-1 99.77%
    Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
    Ceftizoxime sodium
  • HY-P10396
    Elf18 849352-44-9 99.28%
    Elf18 is a peptide fragment of bacterial translation elongation factor Tu (EF-Tu). Elf18 can be recognized by plant pattern recognition receptors, thereby inducing an immune response. Elf18 can enhance plants' resistance to pathogens and can be used in research related to plant immune responses.
    Elf18
  • HY-U00128
    PPA-904 30189-85-6 99.31%
    PPA-904 is a specific phenothiazine photosensitizer in photodynamic research (PDT) research, especially topical application for cutaneous leishmaniasis in vivo.
    PPA-904
Cat. No. Product Name / Synonyms Application Reactivity