2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-132598A
    Miravirsen sodium 99.44%
    Miravirsen sodium is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen sodium is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen sodium inhibits HCV replication, and can be used in research of HCV infection.
    Miravirsen sodium
  • HY-17373S1
    Posaconazole-d4 1133712-26-1 ≥99.0%
    Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
    Posaconazole-d4
  • HY-B0803S1
    Lumefantrine-d9 2477594-24-2
    Lumefantrine-d9 is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.
    Lumefantrine-d9
  • HY-N2041S6
    Myristic acid-d5 327077-03-2 ≥98.0%
    Myristic acid-d5 is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
    Myristic acid-d5
  • HY-W003561
    DHFR-IN-3 137553-43-6 99.48%
    DHFR-IN-3 is a dihydrofolate reductase (DHFR) inhibitor with the IC50 values of 19 μM and 12 μM in rat liver and P. carinii DHFR, respectively.
    DHFR-IN-3
  • HY-W005186
    6-Bromocoumarin 19063-55-9 98%
    6-Bromocoumarin (compound 34) is a potential anti-bacterial agent, with no inhibition against 17β-HSD1. 6-Bromocoumarin exhibtis affinity for α and β estrogen receptors.
    6-Bromocoumarin
  • HY-W008129
    H-D-cis-Hyp-OH 2584-71-6 ≥98.0%
    H-D-cis-Hyp-OH (cis-4-Hydroxy-D-proline) is a proline derivative involved in bacterial metabolic pathways and is a substrate for cis-4-hydroxy-D-proline dehydrogenase. H-D-cis-Hyp-OH is a precursor for the synthesis of conformationally constrained PNA adenine monomers and can be used to study the specificity and kinetics of D-alanine dehydrogenase.
    H-D-cis-Hyp-OH
  • HY-W008216
    HMMNI 936-05-0 99.91%
    HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections.
    HMMNI
  • HY-W008833
    3-Aminobutanoic acid 541-48-0 ≥98.0%
    3-Aminobutanoic acid is a β-amino acid. 3-Aminobutanoic acid can protect plant against a challenge infection with P. infestans. 3-Aminobutanoic acid has various levels of susceptibility for the pathogen.
    3-Aminobutanoic acid
  • HY-W010937
    1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide 174899-83-3 ≥98.0%
    1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (compound 8) is an HIV-1 integrase inhibitor that effectively inhibits both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration reaction. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide can be utilized in HIV-1 research.
    1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide
  • HY-W011733
    Tulobuterol hydrochloride 56776-01-3 99.83%
    Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation.
    Tulobuterol hydrochloride
  • HY-W012738
    DL-Pyroglutamic acid 149-87-1 ≥98.0%
    DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action.
    DL-Pyroglutamic acid
  • HY-W019806
    Lacto-N-fucopentaose I 7578-25-8 ≥98.0%
    Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development.
    Lacto-N-fucopentaose I
  • HY-W074930
    (S)-Tenofovir 147127-19-3 98.34%
    (S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).
    (S)-Tenofovir
  • HY-W395779
    EBOV-IN-1 1335113-30-8
    EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM.
    EBOV-IN-1
  • HY-W436424
    DAM-IN-1 935279-95-1
    DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor, IC50: 48 μM. DMA-IN-1 inhibits Caulobacter growth with an MIC of 35 μM.
    DAM-IN-1
  • HY-Y0264S1
    4-Hydroxybenzoic acid-d4 152404-47-2 ≥99.0%
    4-Hydroxybenzoic acid-d4 is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.
    4-Hydroxybenzoic acid-d4
  • HY-W016819B
    5-Fluoroorotic acid monohydrate 220141-70-8 ≥98.0%
    5-Fluoroorotic acid monohydrate is the monohydrate salt form of 5-Fluoroorotic acid (HY-W016819). 5-Fluoroorotic acid monohydrate is the inhibitor for thymidylate synthase that acts as a selective agent in yeast molecular genetics. 5-Fluoroorotic acid monohydrate exhibits antimalarial activity.
    5-Fluoroorotic acid monohydrate
  • HY-60346
    2-Pyrimidinecarboxylic acid 31519-62-7 99.27%
    2-Pyrimidinecarboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
    2-Pyrimidinecarboxylic acid
  • HY-B0825
    (E)-Fenpyroximate 134098-61-6 99.81%
    (E)-Fenpyroximate is a potent acaricide.
    (E)-Fenpyroximate
Cat. No. Product Name / Synonyms Application Reactivity