2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-122394
    Thiolactomycin 82079-32-1
    Thiolactomycin is an antibiotic. Thiolactomycin is active against Gram-negative anaerobes. Thiolactomycin also inhibits malaria and trypanosomes. Thiolactomycin is a FabB inhibitor. Thiolactomycin inhibits the synthesis of fatty acids and mycolic acids.
    Thiolactomycin
  • HY-124564
    Methisazone 1910-68-5 98.26%
    Methisazone (Marboran) is an antiviral agent that works by inhibiting mRNA and protein synthesis. Methisazone is also a SARS-CoV-2 (COVID-19) inhibitor. Methisazone is mainly used in pox viruses.
    Methisazone
  • HY-124594
    CA inhibitor 1 2189684-45-3 99.77%
    CA inhibitor 1 (GS-6207 analog) is a potent HIV capsid inhibitor for HIV inhibition. CA inhibitor 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CA inhibitor 1
  • HY-124789
    TBT1 52535-76-9 99.29%
    TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM.
    TBT1
  • HY-126396
    Sordarin sodium 463356-00-5 ≥99.0%
    Sordarin sodium is an eEF2 inhibitor and antibiotic. Sordarin sodium's function is dependent on the diphthamide modification on eEF2. Sordarin sodium inhibits protein synthesis by preventing the binding of eEF2 to the ribosome complex. Sordarin sodium has antifungal activity.
    Sordarin sodium
  • HY-128467
    Dehydroacetic acid sodium 4418-26-2 99.87%
    Dehydroacetic acid sodium, a pyrone derivative acts as an antibacterial and antifungal agent. Dehydroacetic acid possess phytotoxic activity.
    Dehydroacetic acid sodium
  • HY-130839
    LolCDE-IN-1 1639933-78-0 99.79%
    LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex, with antibacterial activity.
    LolCDE-IN-1
  • HY-131873
    Dynapyrazole-A 2226517-75-3 98.41%
    Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity.
    Dynapyrazole-A
  • HY-133704
    Pyrrolnitrin 1018-71-9 99.76%
    Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria.
    Pyrrolnitrin
  • HY-134910
    SID-852843 909859-19-4 99.91%
    SID-852843 is a WNV NS2B-NS3 proteinase inhibitor. SID-852843 can inhibit WNV NS2B-NS3 proteinase activity with IC50 value of 0.105 μM. SID-852843 can be used for the research of virus infection.
    SID-852843
  • HY-135072
    N,N',N''-Triacetylchitotriose 38864-21-0 ≥98.0%
    N,N',N''-Triacetylchitotriose is a competitive inhibitor of lysozyme.
    N,N',N''-Triacetylchitotriose
  • HY-135282
    DHODH-IN-1 1800296-63-2 98.65%
    DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway.
    DHODH-IN-1
  • HY-135652
    Hexyl gallate 1087-26-9 99.75%
    Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM.
    Hexyl gallate
  • HY-136450
    Triclabendazole sulfoxide 100648-13-3 98.78%
    Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP.
    Triclabendazole sulfoxide
  • HY-13735D
    d-Atabrine dihydrochloride 56100-41-5 99.64%
    d-Atabrine dihydrochloride is an active enantiomer of quinacrine which displays antiprion activity.
    d-Atabrine dihydrochloride
  • HY-13756S
    Tacrolimus-13C,d2 1356841-89-8 ≥98.0%
    Tacrolimus-13C,d2 is a 13C-labeled and deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.
    Tacrolimus-13C,d2
  • HY-139431
    NAG-thiazoline 179030-22-9
    NAG-thiazoline is a O-GlcNAcase inhibitor with a Ki of 180 nM. NAG-thiazoline is a potent GH20 GlcNAcase (VhGlcNAcase) inhibitor with an IC50 of 11.9 μM and a Ki of 62 µM.
    NAG-thiazoline
  • HY-139684
    MNK1/2-IN-5 1426928-20-2 99.93%
    MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor as a therapeutic agent.
    MNK1/2-IN-5
  • HY-142128
    Cymal-6 228579-27-9 ≥98.0%
    Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an Ki value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant.
    Cymal-6
  • HY-144644
    NS2B/NS3-IN-3 2832876-90-9 98.98%
    NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease.
    NS2B/NS3-IN-3
Cat. No. Product Name / Synonyms Application Reactivity