2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W022973R
    Trinexapac-ethyl (Standard) 95266-40-3
    Trinexapac-ethyl (Standard) is the analytical standard of Trinexapac-ethyl. This product is intended for research and analytical applications. Trinexapac-ethyl (TE) is well-known as an anti-gibberellin plant growth regulator.
    Trinexapac-ethyl (Standard)
  • HY-W040790S
    2,6-Dimethylpyrazine-d6 1335402-00-0 98%
    2,6-Dimethylpyrazine-d6 is deuterated labeled 2,6-Dimethylpyrazine (HY-W040790). 2,6-Dimethylpyrazine is a key aroma compound. 2,6-Dimethylpyrazine can be isolated from Boletus edulis. 2,6-Dimethylpyrazine reduces seminal vesicle weight in rats. 2,6-Dimethylpyrazine can be used in food flavor and reproductive system research.
    2,6-Dimethylpyrazine-d6
  • HY-W050044R
    L-Azetidine-2-carboxylic acid (Standard) 2133-34-8
    L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces ATF6 cleavage and upregulates phosphorylated eIF2α levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects.
    L-Azetidine-2-carboxylic acid (Standard)
  • HY-W089845R
    Heneicosane (Standard) 629-94-7
    Heneicosane (Standard) is the analytical standard of Heneicosane (HY-W089845). This product is intended for research and analytical applications. Heneicosane is a royal-specific pheromone of insects (such as subterranean termites) and is an identification signal for queens and kings in termites. Heneicosane mediates royal recognition and the maintenance of social division of labor by being sensed by worker ants and triggering vibrations and antennal behaviors. Heneicosane can exert anti-inflammatory, analgesic and antipyretic activities by inhibiting the release of inflammatory mediators (such as prostaglandins and cytokines). At the same time, Heneicosane can also inhibit the mycelial growth of aflatoxin-producing fungi and inhibit the production of aflatoxin. Heneicosane can be used in insect chemical ecology research to analyze the regulatory mechanism of termite social behavior, and is also a potential target for new anti-inflammatory drugs.
    Heneicosane (Standard)
  • HY-W108875R
    Mupirocin lithium (Standard) 73346-79-9
    Mupirocin (lithium) (Standard) is the analytical standard of Mupirocin lithium (HY-W108875). This product is intended for research and analytical applications. Mupirocin lithium is an antibiotic. Mupirocin lithium inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin lithium has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin lithium can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis.
    Mupirocin lithium (Standard)
  • HY-W653723R
    N-Nitrosodicyclohexylamine (Standard) 947-92-2
    N-Nitrosodicyclohexylamine (Standard) is the analytical standard of N-Nitrosodicyclohexylamine. This product is intended for research and analytical applications. N-Nitrosodicyclohexylamine (NDCHA) is a N-nitrosocompound with anti-androgenic activities. N-Nitrosodicyclohexylamine shows the competitive binding to androgen receptor (AR) against 5α-dihydrotestosterone and decreased the level of AR protein.
    N-Nitrosodicyclohexylamine (Standard)
  • HY-W698952S
    3β hydroxy Tibolone-d5 98%
    3β hydroxy Tibolone-d5 is deuterium labeled Tibolone. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research.
    3β hydroxy Tibolone-d5
  • HY-W011683S7
    2'-Deoxyadenosine monohydrate-15N5 98%
    2'-Deoxyadenosine monohydrate-15N5 is the 15N labeled 2'-Deoxyadenosine monohydrate (HY-W011683). 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer.
    2'-Deoxyadenosine monohydrate-15N5
  • HY-W014901S1
    Bisphenol F-13C12 1410794-08-9 98%
    Bisphenol F-13C12 is the 13C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260).
    Bisphenol F-13C12
  • HY-W687022AR
    Chloroethene (polymer) (Standard) 9002-86-2
    Chloroethene (polymer) (Standard) is the analytical standard of Chloroethene (polymer) (HY-W687022A). This product is intended for research and analytical applications. Chloroethene polymer (Polyvinyl chloride) is an orally active vinyl chloride polymer. Chloroethene polymer is cytotoxic, reproductively toxic, and an endocrine disruptor. Chloroethene polymer can be used in the research of packaging inner surfaces, food wrapping paper, agricultural crop coverings, and plastic bottles.
    Chloroethene (polymer) (Standard)
  • HY-107533
    T-98475 199119-18-1 98%
    T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.2 nM.
    T-98475
  • HY-P0236
    Neurokinin A(4-10) 97559-35-8 98%
    Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.
    Neurokinin A(4-10)
  • HY-P0250
    Kassinin 63968-82-1 98%
    Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved in neuropeptide signalling.
    Kassinin
  • HY-P0255
    Physalaemin 2507-24-6 98%
    Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with high affinity.
    Physalaemin
  • HY-U00207
    MEN11467 214487-46-4 98%
    MEN11467 is a selective and orally- effective peptidomimetic tachykinin NK1 receptor antagonist.
    MEN11467
  • HY-U00220
    KAT681 373641-87-3 98%
    KAT681 is a liver-selective thyromimetic.
    KAT681
  • HY-U00303
    Trecadrine 90845-56-0 98%
    Trecadrine is a β3-adrenergic agonist.
    Trecadrine
  • HY-101690
    QF0301B 149247-12-1 98%
    QF0301B is an α1 adrenergic receptor antagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.
    QF0301B
  • HY-U00104
    YM-46303 171722-81-9 98%
    YM-46303 is an mAChR antagonist which exhibits the highest affinities for M1 and M3 receptors, and selectivity for M3 over M2 receptor.
    YM-46303
  • HY-U00110
    MG 1 148274-76-4 98%
    MG 1 is an α1 adrenergic receptor antagonist.
    MG 1
Cat. No. Product Name / Synonyms Application Reactivity