2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W750129
    (3E,8Z)-3,8-Tetradecadienyl acetate 163041-87-0 98%
    (3E,8Z)-3,8-Tetradecadienyl acetate is an insect sex pheromone that can be isolated from unmated female South American potato tuber moths (Scrobipalpula absoluta).
    (3E,8Z)-3,8-Tetradecadienyl acetate
  • HY-W751431
    (E,Z)-4,7-Tridecadienyl acetate 57981-60-9 98%
    (E,Z)-4,7-Tridecadienyl acetate is a sex pheromone that can be isolated from potato tuber moths (Phthorimaea opercucella).
    (E,Z)-4,7-Tridecadienyl acetate
  • HY-W751574
    Elagolix-d6 sodium 98%
    Elagolix-d6 (sodium) (NBI-56418-d6 (sodium)) is deuterium labeled Elagolix sodium. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
    Elagolix-d6 sodium
  • HY-W752055
    (Rac)-Nebivolol-d4 hydrochloride 2701283-32-9 98%
    (Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC50 of 0.8 nM.
    (Rac)-Nebivolol-d4 hydrochloride
  • HY-W753141
    p,p'-DDE-13C12 201612-50-2 98%
    p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
    p,p'-DDE-13C12
  • HY-W753500
    (E,E)-9,11-Tetradecadienyl acetate 54664-98-1 98%
    (E,E)-9,11-Tetradecadienyl acetate is a female sex pheromone isolated from light-induced isomerization products in female coastal noctuid moths.
    (E,E)-9,11-Tetradecadienyl acetate
  • HY-W777166
    Aprepitant-13C2,d2 (Major) 1217676-37-3 98%
    Aprepitant-13C2,d2 (Major) (MK-0869-13C2,d2) is 13C labeled Aprepitant. Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
    Aprepitant-13C2,d2 (Major)
  • HY-W777963
    (2E)-Octadecenal 51534-37-3 98%
    (2E)-Octadecenal is a female pheromone targeting Lepidoptera insects, isolated from female Tineola bisselliella.
    (2E)-Octadecenal
  • HY-W778391
    Bisphenol A-13C2 263261-64-9 98%
    Bisphenol A-13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders.
    Bisphenol A-13C2
  • HY-W778833
    (Z)-11-Octadecen-1-ol 62972-93-4 98%
    (Z)-11-Octadecen-1-ol is a marking secretion deposited by wasps on repeated flight paths, isolated from the paired labial glands of North American male bumblebees.
    (Z)-11-Octadecen-1-ol
  • HY-W778834
    (Z)-13-Octadecen-1-ol 69820-27-5 98%
    (Z)-13-Octadecen-1-ol is an insect sex pheromone used for trapping sugarcane stem borers (Chilo sacchariphagus).
    (Z)-13-Octadecen-1-ol
  • HY-W779504
    b-Cortolone 667-66-3 98%
    b-Cortolone is the metabolite of Cortisol (HY-N0583), that reveals relatively low biological activity.
    b-Cortolone
  • HY-W780779
    (Z)-12-Nonadecen-9-one 63408-45-7 98%
    (Z)-12-Nonadecen-9-one is a sex pheromone attractive to male raspberry bud moths (Heterocrossa rubophaga).
    (Z)-12-Nonadecen-9-one
  • HY-W780784
    (Z,Z)-3,13-Octadecadien-1-ol 66410-24-0 98%
    (Z,Z)-3,13-Octadecadien-1-ol is an insect sex pheromone used for trapping redwood resin borers (Synanthedon sequoiae (Edwards)).
    (Z,Z)-3,13-Octadecadien-1-ol
  • HY-W780787
    (E,Z)-3,13-Octadecadienyl acetate 53120-26-6 98%
    (E,Z)-3,13-Octadecadienyl acetate (E3,Z13-18:Ac) is an insect sex pheromone that elicits attraction in male lesser peachtree borers (Lesser Peachtree Borer), which can be isolated from female lesser peachtree borers.
    (E,Z)-3,13-Octadecadienyl acetate
  • HY-W780808
    (E)-10-Dodecenol 35237-63-9 98%
    (E)-10-Dodecenol is a sex pheromone capable of eliciting electroantennographic responses in male pea moths.
    (E)-10-Dodecenol
  • HY-W780813
    (Z)-3-Decenol 10340-22-4 98%
    (Z)-3-Decenol is an insect sex pheromone that specifically attracts male beetles.
    (Z)-3-Decenol
  • HY-100607AR
    Landiolol hydrochloride (Standard) 144481-98-1
    Landiolol (ONO1101) hydrochloride (Standard) is the analytical standard of Landiolol hydrochloride (HY-100607A). This product is intended for research and analytical applications. Landiolol (ONO1101) hydrochloride is a highly selective, ultra-short-acting competitive inhibitor of β1 adrenergic receptors. Landiolol hydrochloride specifically blocks cardiac β1 receptors, reducing heart rate and myocardial oxygen consumption. Landiolol hydrochloride inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol hydrochloride has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol hydrochloride can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury.
    Landiolol hydrochloride (Standard)
  • HY-100973AR
    Adenosine 5′-diphosphoribose sodium (Standard) 68414-18-6
    Adenosine 5′-diphosphoribose (sodium) (Standard) is the analytical standard of Adenosine 5′-diphosphoribose (sodium). This product is intended for research and analytical applications. Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5′-diphosphoribose sodium is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5′-diphosphoribose sodium also can enhance autophagy.
    Adenosine 5′-diphosphoribose sodium (Standard)
  • HY-101355AR
    CGP 20712 dihydrochloride (Standard) 1216905-73-5 98%
    CGP 20712 (dihydrochloride) (Standard) is the analytical standard of CGP 20712 (dihydrochloride). This product is intended for research and analytical applications. CGP 20712 dihydrochloride is a highly selective β1-adrenoceptor antagonist with an IC50 of 0.7 nM. CGP 20712 dihydrochloride exhibits ~10,000-fold selectivity over β2-adrenoceptors.
    CGP 20712 dihydrochloride (Standard)
Cat. No. Product Name / Synonyms Application Reactivity