2. Cell Cycle/DNA Damage Apoptosis Metabolic Enzyme/Protease
  3. CDK Caspase Bcl-2 Family Mitochondrial Metabolism Apoptosis
  4. α-Turmerone

α-turmerone is a turmerone. α-turmerone can be isolated from Curcuma longa. α-turmerone decreases the expression of cyclin D1, pro-caspases-3 and -8 and down-regulates Bcl-2 expression. α-turmerone causes mitochondrial transmembrane depolarization. α-turmerone induces Apoptosis. α-turmerone has immunostimulatory effects. α-turmerone has anti-cancer activity against liver cancer and breast cancer.

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α-Turmerone

α-Turmerone Chemical Structure

CAS No. : 82508-15-4

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α-Turmerone Related Antibodies

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Description

α-turmerone is a turmerone. α-turmerone can be isolated from Curcuma longa. α-turmerone decreases the expression of cyclin D1, pro-caspases-3 and -8 and down-regulates Bcl-2 expression. α-turmerone causes mitochondrial transmembrane depolarization. α-turmerone induces Apoptosis. α-turmerone has immunostimulatory effects. α-turmerone has anti-cancer activity against liver cancer and breast cancer[1].

IC50 & Target[1]

Bcl-2

 

Caspase-8

 

Procaspase-3

 

Molecular Weight

218.33

Formula

C15H22O
CAS No.
SMILES

C/C(C)=C\C(CC(C1C=CC(C)=CC1)C)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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α-Turmerone Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Turmerone82508-15-4CDKCaspaseBcl-2 FamilyMitochondrial MetabolismApoptosisCyclin dependent kinaseMDAMB-231anti-proliferativeimmunomodulatoryHepG2MCF-7Inhibitorinhibitorinhibit

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