2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Stem Cell/Wnt
  3. LXR RAR/RXR Wnt β-catenin
  4. UAB116

UAB116 is a Liver X Receptor (LXR)/Retinoid X Receptor (RXR) agonist. UAB116 can decreases metastatic phenotype in hepatoblastoma by inhibiting the Wnt/β-Catenin pathway via upregulation of TRIM29. UAB116 can reduce proliferation, stemness and invasiveness of metastatic hepatoblastoma cells.

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UAB116

UAB116 Chemical Structure

CAS No. : 3031463-59-6

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UAB116 Related Antibodies

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Description

UAB116 is a Liver X Receptor (LXR)/Retinoid X Receptor (RXR) agonist. UAB116 can decreases metastatic phenotype in hepatoblastoma by inhibiting the Wnt/β-Catenin pathway via upregulation of TRIM29. UAB116 can reduce proliferation, stemness and invasiveness of metastatic hepatoblastoma cells[1].

Molecular Weight

370.57

Formula

C25H38O2
CAS No.
SMILES

CCC(C)C(CCC/C1=C\C(C)=C/C=C/C(C)=C/C(O)=O)=C1CCC(C)C
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Room temperature in continental US; may vary elsewhere.
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UAB116 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UAB1163031463-59-6UAB 116UAB-116LXRRAR/RXRWntβ-cateninLiver X receptorRetinoic acid receptorsRetinoid X receptorsBeta cateninInhibitorinhibitorinhibit

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