2. Apoptosis
  3. Apoptosis
  4. Torularhodin

Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer.

For research use only. We do not sell to patients.

Torularhodin Chemical Structure

Torularhodin Chemical Structure

CAS No. : 514-92-1

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Torularhodin Related Antibodies

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Description

Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer[1].

In Vivo

Torularhodin (9-18 mg/kg; p.o; every day; for 10 weeks) inhibits the growth of prostate cancer in nude mice and suggest that such an action is associated the apoptosis of tumor cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Four to six-week-old BALB/c nude mice (male, 18-22 g) were subcutaneously injected with PC-3 cells (5 × 105 cells)[1]
Dosage: 9 mg/kg, 18 mg/kg
Administration: p.o; every day; 2 weeks before transplantation; 7 weeks after transplantation
Result: Lowered the mean number of tumors.
Tumor degeneration, apoptosis and necrosis presented at the end of the experiment.
Increased the mRNA expressions of caspase-3, 8 and 9 in tumor tissues.
Showed Bcl-2 expression of the control group was higher than that of the carotenoid-treated group while the expression of Bax was lower than the carotenoid-treated group.
Molecular Weight

564.84

Formula

C40H52O2
CAS No.
SMILES

OC(/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)=O
Structure Classification
Initial Source

Rhodotorula rubra
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Torularhodin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Torularhodin514-92-1Apoptosiscarotenoidanti-cancer activityapopotsisprostate cancerInhibitorinhibitorinhibit

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