2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. TKA-731

TKA-731 is an NK1 receptor antagonist. TKA-731 can reverse mechanical hyperalgesia. TKA-731 can be used for research on neuropathic pain.

For research use only. We do not sell to patients.

TKA-731

TKA-731 Chemical Structure

CAS No. : 210776-01-5

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TKA-731 Related Antibodies

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Description

TKA-731 is an NK1 receptor antagonist. TKA-731 can reverse mechanical hyperalgesia. TKA-731 can be used for research on neuropathic pain[1].

IC50 & Target[1]

NK1R

 

Molecular Weight

573.68

Formula

C35H35N5O3
CAS No.
SMILES

O=C(N([C@H](C(N(C)CC1=CC=CC=C1)=O)CC2=CC=C(C=CC=C3)C3=C2)C)[C@H](CCC4)N4C5=NC(C6=CC=CC=C6N5)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TKA-731 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TKA-731210776-01-5TKA731TKA 731Neurokinin ReceptorNK receptorTachykinin receptorNK1hyperalgesianeuropathic painInhibitorinhibitorinhibit

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