2. Neuronal Signaling
  3. Beta-secretase Amyloid-β
  4. TAK-070 hydrochloride hydrate

TAK-070 (hydrochloride hydrate) is a noncompetitive and orally active BACE1 inhibitor (IC50 = 3.15 μM). TAK-070 (hydrochloride hydrate) can be used for research of Alzheimer’s disease (AD). TAK-070 (hydrochloride hydrate) inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model.

For research use only. We do not sell to patients.

TAK-070 hydrochloride hydrate

TAK-070 hydrochloride hydrate Chemical Structure

CAS No. : 365276-12-6

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Other Forms of TAK-070 hydrochloride hydrate:

TAK-070 hydrochloride hydrate Related Antibodies

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Description

TAK-070 (hydrochloride hydrate) is a noncompetitive and orally active BACE1 inhibitor (IC50 = 3.15 μM). TAK-070 (hydrochloride hydrate) can be used for research of Alzheimer’s disease (AD). TAK-070 (hydrochloride hydrate) inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].

IC50 & Target[1]

BACE1

 

Molecular Weight

440.02

Formula

C27H34ClNO2
CAS No.
SMILES

CN(C)CC[C@H]1CC2=C(C=C(OCC3=CC=C(C4=CC=CC=C4)C=C3)C=C2)CC1.Cl.O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TAK-070 hydrochloride hydrate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAK-070 hydrochloride365276-12-6Beta-secretaseAmyloid-βBACEβ-Secretase β-amyloid peptideAβAbetaorally activeAlzheimer’sAD modelsoluble AβInhibitorinhibitorinhibit

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