SUN-N8075 dimethanesulfonate 

SUN-N8075 (dimethanesulfonate) is a radical scavenger with antioxidant and neuroprotective effect. SUN-N8075 (dimethanesulfonate) can inhibit apoptosis and ROS production. SUN-N8075 (dimethanesulfonate) can protect against 6-OHDA (HY-B1081)-induced cell death. SUN-N8075 (dimethanesulfonate) can be used for the research of neurological disease, such as Parkinson's disease^[1][2].

SUN-N8075 (dimethanesulfonate) (10-30 mg/kg, i.p., twice) shows protective effect against the MPTP (HY-W114750)-induced decrease in TH-positive cells in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

669.82

C₃₁H₄₄FN₃O₈S₂

224450-56-0

CC(C(C)=C(N)C(C)=C1)=C1OC[C@@H](O)CN(CC2)CCN2C(C=C3)=CC=C3CC4=CC=C(F)C=C4.CS(=O)(O)=O.CS(=O)(O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Oyagi A, et al. Protective effects of SUN N8075, a novel agent with antioxidant properties, in in vitro and in vivo models of Parkinson's disease. Brain Res. 2008 Jun 12;1214:169-76.

  [2]. Akane M, et al. SUN N8075, a novel radical scavenger, protects against retinal cell death in mice. Neurosci Lett. 2011 Jan 13;488(1):87-91.