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Results for "

very-long-chain

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ELOVL (3) Apoptosis (2) Bacterial (4) Biochemical Assay Reagents (4) Cytochrome P450 (3) DNA/RNA Synthesis (3) Drug Intermediate (1) Endogenous Metabolite (11) Herbicide (3) Insulin Receptor (2) Isotope-Labeled Compounds (3) PI3K (3) PKC (1) Reactive Oxygen Species (2) Reference Standards (1) RXFP Receptor (2) Thyroid Hormone Receptor (1) TNF Receptor (1) Wnt (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (4) Inflammation/Immunology (1) Metabolic Disease (16) Neurological Disease (7)

Inhibitors & Agonists

Biochemical Assay Reagents

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Isotope-Labeled Compounds

Antibodies

Targets Recommended: ELOVL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010629

2-Chloroacetamide 1 Publications Verification	Bacterial	Infection
2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase .

HY-N8425

Octacosanoic acid Montanic acid	Endogenous Metabolite	Metabolic Disease
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-W010629R

2-Chloroacetamide (Standard)	Reference Standards Bacterial	Infection
2-Chloroacetamide (Standard) is the analytical standard of 2-Chloroacetamide. This product is intended for research and analytical applications. 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase .

HY-W010629S

2-Chloroacetamide-d4	Bacterial	Infection
2-Chloroacetamide-d₄ is the deuterium labeled 2-Chloroacetamide . 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase .

HY-N8425R

Octacosanoic acid (Standard)	Endogenous Metabolite	Metabolic Disease
Octacosanoic acid (Standard) is the analytical standard of Octacosanoic acid. This product is intended for research and analytical applications. Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-CE01045

3-Hydroxytetracosanoyl-CoA 3-Hydroxytetracosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxytetracosanoyl-CoA (3-Hydroxytetracosanoyl-coenzyme A) is a very long-chain fatty acyl-CoA.

HY-E70276

Heneicosanoyl-CoA	Endogenous Metabolite	Metabolic Disease
Heneicosanoyl-CoA is a substrate of Very long-chain acyl-CoA dehydrogenase (VLCAD) in the anaerobic electron transfer flavoprotein (ETF) assay .

HY-CE00395

(S)-3-Hydroxyhexacosanoyl-CoA (S)-3-Hydroxyhexacosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(S)-3-Hydroxyhexacosanoyl-CoA ((S)-3-Hydroxyhexacosanoyl-coenzyme A) is a very long-chain hydroxy fatty acyl-CoA.

HY-120958

Nisinic acid C24:6n-3	Endogenous Metabolite	Metabolic Disease
Nisinic acid (C24:6n-3) is a very long chain polyunsaturated fatty acid (VLCPUFA) that is a component of triglycerides and cholesterol esters in mouse and rat testis .

HY-121423

Dimethachlor	Apoptosis Reactive Oxygen Species	Metabolic Disease
Dimethachlor, a synthetic herbicide, inhibits the undesirable growth of weeds via the suppression of very long-chain fatty acid synthesis. Dimethachlor disrupts normal developmental processes via the induction of apoptosis and ROS production .

HY-122129

Dotriaconta-14,17,20,23,26,29-hexaenoic acid	Endogenous Metabolite	Metabolic Disease
Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain. Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration. Dotriaconta-14,17,20,23,26,29-hexaenoic acid is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina.

HY-145272

ELOVL1-IN-3	ELOVL	Neurological Disease
ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of *elongation of very long* chain fatty acid 1 (ELOVL1**) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD) ^[1].

HY-121423R

Dimethachlor (Standard)	Apoptosis Reactive Oxygen Species	Metabolic Disease
Dimethachlor (Standard) is the analytical standard of Dimethachlor. This product is intended for research and analytical applications. Dimethachlor, a synthetic herbicide, inhibits the undesirable growth of weeds via the suppression of very long-chain fatty acid synthesis. Dimethachlor disrupts normal developmental processes via the induction of apoptosis and ROS production .

HY-136373

Metazachlor BAS 479H	Herbicide Cytochrome P450 DNA/RNA Synthesis	Others
Metazachlor (BAS 479H) is a herbicide belonging to the chloroacetamides class. Metazachlor can inhibit the synthesis of very long chain fatty acids during the germination and emergence of weed seeds, thereby interfering with cell division and tissue differentiation, and thus hindering the normal growth and development of weeds .

HY-N7109

Erucic acid 1 Publications Verification	PI3K Endogenous Metabolite	Neurological Disease
Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia .

HY-N7109B

Erucic acid sodium	PI3K Endogenous Metabolite	Neurological Disease
Erucic acid sodium, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid sodium can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid sodium can improve cognitive impairment and be effective against dementia .

HY-122129S

Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d6	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d₆ is deuterium labeled Dotriaconta-14,17,20,23,26,29-hexaenoic acid. Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain. Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration. Dotriaconta-14,17,20,23,26,29-hexaenoic acid is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina .

HY-E70254

Tricosanoyl-CoA triammonium	Others	Others
Tricosanoyl-CoA triammonium is a very long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A (HY-128851) with the carboxy group of tricosanoic acid (HY-W009081). Tricosanoyl-CoA is functionally related to a tricosanoic acid. Tricosanoyl-CoA is a conjugate acid of a tricosanoyl-CoA(4-).

HY-145122

ELOVL1-IN-1 1 Publications Verification	ELOVL	Metabolic Disease
ELOVL1-IN-1 is an ELOVL1 inhibitor extracted from patent WO2018107056A1, compound 87. ELOVL1-IN-1 can reduce very long chain fatty acid levels. ELOVL1-IN-1 can be used for the research of adrenoleukodystrophy (ALD) .

HY-156679

VK-0214	Thyroid Hormone Receptor	Neurological Disease Cancer
VK-0214 is an agonist of the thyroid β receptor (TRβ). By activating the expression of ABCD2, it can reduce the accumulation of very long-chain fatty acids (VLCFAs) and further alleviate glioblastoma multiforme. VK-0214 has the effect of regulating fatty acid metabolism and can be used in the research of X-linked adrenoleukodystrophy (X-ALD) .

HY-N7109R

Erucic acid (Standard)	PI3K Endogenous Metabolite	Neurological Disease
Erucic acid (Standard) is the analytical standard of Erucic acid. This product is intended for research and analytical applications. Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia .

HY-145270

ELOVL1-IN-2	ELOVL	Metabolic Disease
ELOVL1-IN-2 is an elongation of very long chain fatty acid 1 (ELOVL1) enzyme inhibitor, ELOVL1-IN-2 shows weak ELOVL1 inhibition (IC₅₀=21 μM) and moderate potency in a primary cellular assay (HEK293 C26 IC₅₀=6.7 μM) .

HY-136373S

Metazachlor-d6 BAS 479H-d₆	Isotope-Labeled Compounds Herbicide Cytochrome P450 DNA/RNA Synthesis	Others
Metazachlor-d₆ (BAS 479H-d₆) is a deuterium labeled Metazachlor (HY-136373). Metazachlor (BAS 479H) is a herbicide belonging to the chloroacetamides class. Metazachlor can inhibit the synthesis of very long chain fatty acids during the germination and emergence of weed seeds, thereby interfering with cell division and tissue differentiation, and thus hindering the normal growth and development of weeds .

HY-136373R

Metazachlor (Standard) BAS 479H (Standard)	Herbicide Cytochrome P450 DNA/RNA Synthesis	Others
Metazachlor (Standard) (BAS 479H (Standard)) is the analytical standard of Metazachlor (HY-136373). This product is intended for research and analytical applications. Metazachlor (BAS 479H) is a herbicide belonging to the chloroacetamides class. Metazachlor can inhibit the synthesis of very long chain fatty acids during the germination and emergence of weed seeds, thereby interfering with cell division and tissue differentiation, and thus hindering the normal growth and development of weeds .

HY-158575

all-cis-14,17,20,23,26,29-Dotriacontahexaenol 14(Z),17(Z),20(Z),23(Z),26(Z),29(Z)-Dotriacontahexaenol	Drug Intermediate	Others
all-cis-14,17,20,23,26,29-Dotriacontahexaenol (14(Z),17(Z),20(Z),23(Z),26(Z),29(Z)-Dotriacontahexaenol) is a long-chain fatty alcohol. It is an intermediate in the synthesis of the very long-chain PUFA all-cis-14,17,20,23,26,29-dotriacontahexaenoic acid .

HY-117057

Hexaenoic acid	Endogenous Metabolite	Metabolic Disease
Very long chain polyunsaturated fatty acids (VLCPUFAs) are important components of ceramides and sphingomyelin and are present in retina, sperm, and brain. Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic acid is a C34:6 VLCPUFA whose specific biological actions are largely unknown. This VLCPUFA, along with others, has been investigated for its role in activating protein kinase C.

HY-117057S

Hexaenoic acid-d6	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Hexaenoic acid-d₆ is deuterium labeled Hexaenoic acid. Very long chain polyunsaturated fatty acids (VLCPUFAs) are important components of ceramides and sphingomyelin and are present in retina, sperm, and brain. Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic acid is a C34:6 VLCPUFA whose specific biological actions are largely unknown. This VLCPUFA, along with others, has been investigated for its role in activating protein kinase C .

HY-N7864

Osbond acid all-cis-4,7,10,13,16-Docosapentaenoic acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-P4062

Insulin peglispro BIL	Insulin Receptor	Metabolic Disease
Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins .

HY-P4890A

Relaxin H3 (human) (TFA)	RXFP Receptor	Neurological Disease
Relaxin H3 (human) (TFA) is a kind of relaxin peptide. Relaxin H3 (human) (TFA) exerts antifibrotic actions via RXFP1 .

HY-P4890

Relaxin H3 (human)	RXFP Receptor	Neurological Disease
Relaxin H3 (human) is a kind of relaxin peptide. Relaxin H3 (human) exerts antifibrotic actions via RXFP1 .

HY-P10693

CZEN-002	TNF Receptor Bacterial	Infection Inflammation/Immunology
CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α .

HY-P10204

FZD7 antagonist 1	Wnt	Cancer
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC₅₀ value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .

HY-P3479

Insulin (swine)	Insulin Receptor	Metabolic Disease
Insulin (swine) is a porcine-derived insulin used in diabetes research .

HY-P1372

PKC ζ pseudosubstrate	PKC	Others
PKC ζ pseudosubstrate, a PKC ζ inhibitor peptide, can be attached to cell permeabilization vector peptide .

HY-P3432

DfTat	Biochemical Assay Reagents	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

Cat. No.	Product Name	Type

HY-N7864

Osbond acid all-cis-4,7,10,13,16-Docosapentaenoic acid	Cell Assay Reagents
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

Osbond acid

all-cis-4,7,10,13,16-Docosapentaenoic acid

Cell Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

Insulin (swine)	Insulin Receptor	Metabolic Disease
Insulin (swine) is a porcine-derived insulin used in diabetes research .

DfTat	Biochemical Assay Reagents	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

Insulin peglispro BIL	Insulin Receptor	Metabolic Disease
Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins .

Relaxin H3 (human) (TFA)	RXFP Receptor	Neurological Disease
Relaxin H3 (human) (TFA) is a kind of relaxin peptide. Relaxin H3 (human) (TFA) exerts antifibrotic actions via RXFP1 .

Relaxin H3 (human)	RXFP Receptor	Neurological Disease
Relaxin H3 (human) is a kind of relaxin peptide. Relaxin H3 (human) exerts antifibrotic actions via RXFP1 .

CZEN-002	TNF Receptor Bacterial	Infection Inflammation/Immunology
CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α .

FZD7 antagonist 1	Wnt	Cancer
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC₅₀ value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8425

Octacosanoic acid Montanic acid	Structural Classification Croton caudatus Geisel. Croton. Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Euphorbiaceae Plants Disease Research Fields	Endogenous Metabolite
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-N7109

Erucic acid 1 Publications Verification	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Plants Isatis indigotica Fortune Brassicaceae Endogenous metabolite Raphanus sativus Linn.	PI3K Endogenous Metabolite
Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia .

HY-N8425R

Octacosanoic acid (Standard)	Structural Classification Croton caudatus Geisel. Croton. Ketones, Aldehydes, Acids Source classification Euphorbiaceae Plants	Endogenous Metabolite
Octacosanoic acid (Standard) is the analytical standard of Octacosanoic acid. This product is intended for research and analytical applications. Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-N7109B

Erucic acid sodium	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Brassicaceae Raphanus sativus Linn.	PI3K Endogenous Metabolite
Erucic acid sodium, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid sodium can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid sodium can improve cognitive impairment and be effective against dementia .

HY-N7109R

Erucic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Plants Isatis indigotica Fortune Brassicaceae Endogenous metabolite Raphanus sativus Linn.	PI3K Endogenous Metabolite
Erucic acid (Standard) is the analytical standard of Erucic acid. This product is intended for research and analytical applications. Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia .

Cat. No.	Product Name	Chemical Structure

HY-W010629S

2-Chloroacetamide-d4
2-Chloroacetamide-d₄ is the deuterium labeled 2-Chloroacetamide . 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase .

HY-122129S

Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d6

Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d₆ is deuterium labeled Dotriaconta-14,17,20,23,26,29-hexaenoic acid. Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain. Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration. Dotriaconta-14,17,20,23,26,29-hexaenoic acid is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina .

HY-136373S

Metazachlor-d6

Metazachlor-d₆ (BAS 479H-d₆) is a deuterium labeled Metazachlor (HY-136373). Metazachlor (BAS 479H) is a herbicide belonging to the chloroacetamides class. Metazachlor can inhibit the synthesis of very long chain fatty acids during the germination and emergence of weed seeds, thereby interfering with cell division and tissue differentiation, and thus hindering the normal growth and development of weeds .

HY-117057S

Hexaenoic acid-d6

Hexaenoic acid-d₆ is deuterium labeled Hexaenoic acid. Very long chain polyunsaturated fatty acids (VLCPUFAs) are important components of ceramides and sphingomyelin and are present in retina, sperm, and brain. Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic acid is a C34:6 VLCPUFA whose specific biological actions are largely unknown. This VLCPUFA, along with others, has been investigated for its role in activating protein kinase C .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81813

	ELOVL5 Antibody (YA1558) ELOVL FA elongase 5; Fatty acid elongase 1; hELO1; very long chain 3-ketoacyl-CoA synthase 5	WB, ICC/IF	Human
	ELOVL5 Antibody (YA1558) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1558), targeting ELOVL5, with a predicted molecular weight of 35 kDa (observed band size: 35 kDa). ELOVL5 Antibody (YA1558) can be used for WB, ICC/IF experiment in human background.

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