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urinary system diseases

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15574
    Piboserod
    4 Publications Verification

    SB-207266

    5-HT Receptor Cardiovascular Disease
    Piboserod is an orally available selective antagonist of the 5-HT4 receptor, with a Ki value of approximately 0.1 nM for human 5-HT4 receptors. Piboserod can competitively bind to the 5-HT4 receptor and block the activation of the 5-HT4 receptor. Piboserod can inhibit the enhancing effect of 5-HT on the nerve-mediated contraction response of the human bladder detrusor muscle. Piboserod is mainly used in the research of urinary system diseases (such as overactive bladder) and cardiovascular diseases (such as chronic heart failure) .
    Piboserod
  • HY-120473

    Adrenergic Receptor Endocrinology
    TAK-259 is an orally active and selective α1D adrenoceptor (α1D-AR) antagonist with a Ki value of 1.1 nM. TAK-259 inhibits excessive contraction of bladder smooth muscle and prolongs voiding intervals. TAK-259 is promising for research of urinary system diseases .
    TAK-259
  • HY-177544

    Prostaglandin Receptor Endocrinology
    EP1 receptor antagonist-1 (Compound Example 5a freebase) is an EP1 prostaglandin receptor antagonist. EP1 receptor antagonist-1 is promising for research of urinary system-related diseases .
    EP1 receptor antagonist-1
  • HY-15574R

    5-HT Receptor Cardiovascular Disease
    Piboserod (Standard) is the analytical standard of Piboserod. This product is intended for research and analytical applications. Piboserod is an orally available selective antagonist of the 5-HT4 receptor, with a Ki value of approximately 0.1 nM for human 5-HT4 receptors. Piboserod can competitively bind to the 5-HT4 receptor and block the activation of the 5-HT4 receptor. Piboserod can inhibit the enhancing effect of 5-HT on the nerve-mediated contraction response of the human bladder detrusor muscle. Piboserod is mainly used in the research of urinary system diseases (such as overactive bladder) and cardiovascular diseases (such as chronic heart failure) .
    Piboserod (Standard)

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